TPM1
-
Official Full Name
tropomyosin 1 (alpha) -
Overview
The protein contains the Treponema pallidum membrane protein A immunodominant regions. The protein is purified by proprietary chromatographic technique. -
Synonyms
TPM1;tropomyosin 1 (alpha);C15orf13, cardiomyopathy, hypertrophic 3 , chromosome 15 open reading frame 13 , CMH3;tropomyosin alpha-1 chain;alpha-tropomyosin;sarcomeric tropomyosin kappa;cardiomyopathy, hypertrophic 3;tropomyosin 1 (alpha) isoform;TmpA;tmpA membrane protein
Recombinant Proteins
- Human
- Treponema Pallidum
- Zebrafish
- Mouse
- Chicken
- Treponema pallidum
- Rabbit
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Insect Cell
- E. coli
- Yeast
- His
- Non
- Myc&DDK
- His&Myc
- His&Fc&Avi
Involved Pathway
TPM1 involved in several pathways and played different roles in them. We selected most pathways TPM1 participated on our site, such as Cardiac muscle contraction,Adrenergic signaling in cardiomyocytes,MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with TPM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adrenergic signaling in cardiomyocytes | AKT2,ATP1B2A,ADCY7,CAMK2D,ATP1A3B,ATP1B4,PIK3R3B,PPP2R5B,ACTC1A,CALM |
| MicroRNAs in cancer | ITGA5,PLAU,MAPK1,PRKCE,APC,DNMT3B,SOX4,BMI1,WNT3,KIF23 |
| Hypertrophic cardiomyopathy (HCM) | TGFB3,ITGA5,ITGA10,SGCG,ITGB3,TPM4,ITGB7,ITGA8,ITGB1,LAMA2 |
| Dilated cardiomyopathy | Adcy4,CACNB1,ITGB8,CACNG3,PRKACG,TGFB2,CACNB4,ADRB1,TNF,CACNB2 |
| Cardiac muscle contraction | COX6B2,TNNC1,ATP2A2,ATP1A2A,ATP1B3B,ATP1A2,TPM2,CACNG6A,UQCRFS1,CACNG3 |
Protein Function
TPM1 has several biochemical functions, for example, actin binding,cytoskeletal protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TPM1 itself. We selected most functions TPM1 had, and list some proteins which have the same functions with TPM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytoskeletal protein binding | PKD2,EZRA,NF2A,DES,ABI1,PTPN4A,ACTN2,ANXA2B,LIN7C,RPH3AL |
| structural constituent of cytoskeleton | TUBA1L2,COX4I2,TUBGCP2,TUBB2,KRT2,TUBA4A,ACTA1,TUBA1L,TUBA1A,CTNNA2 |
| structural constituent of muscle | SORBS2,OBSCN,TPM4,NEBL,TPM2,ACTN2,COX4I2,CAPN3,MYL6B,ANKRD2 |
| actin binding | PLEC,PARVG,TWF1B,HIP1,WASB,MYO1H,WASF3B,ABLIM3,TNNI1,EPS8L2 |
| protein binding | SULT1B1,FHOD1,HDAC1,RASSF4,AHCY,ZC3H14,GPI1,PAK3,KCTD9,ODC1 |
Interacting Protein
TPM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TPM1.
TNNT1;KXD1;GOLGA2;SYCE1;C1orf216;CAGE1
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