TNRC6A
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Official Full Name
trinucleotide repeat containing 6A -
Overview
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. -
Synonyms
TNRC6A;trinucleotide repeat containing 6A;TNRC6, trinucleotide repeat containing 6;trinucleotide repeat-containing gene 6A protein;CAGH26;GW182;KIAA1460;EDIE;GW182 autoantigen;CAG repeat protein 26;EMSY interactor protein;glycine-tryptophan pr
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TNRC6A-8080H | Recombinant Human TNRC6A protein, His & T7-tagged | E.coli | Human | His&T7 | Thr1670~Met1962 |
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| Tnrc6a-8081M | Recombinant Mouse Tnrc6a protein, His & T7-tagged | E.coli | Mouse | His&T7 | Thr1605~Met1896 |
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Involved Pathway
TNRC6A involved in several pathways and played different roles in them. We selected most pathways TNRC6A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TNRC6A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TNRC6A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TNRC6A itself. We selected most functions TNRC6A had, and list some proteins which have the same functions with TNRC6A. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
TNRC6A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNRC6A here. Most of them are supplied by our site. Hope this information will be useful for your research of TNRC6A.
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References
- Li, SQ; Lian, SL; et al. Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing. JOURNAL OF CELL SCIENCE 121:4134-4144(2008).
