TNKS2
-
Official Full Name
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 -
Synonyms
TNKS2;tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2;tankyrase-2;PARP 5b;PARP 5c;PARP5B;PARP5C;pART6;TANK2;TNKL;TNKS-2;tankyrase 2;tankyrase II;tankyrase-like protein;tankyrase-related protein;poly [ADP-ribose] polymerase 5B;TRF1-interacting ankyrin-related ADP-ribose polymerase 2;PARP-5b;PARP-5c
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cell
- Wheat Germ
- E. coli
- HEK293
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
TNKS2 involved in several pathways and played different roles in them. We selected most pathways TNKS2 participated on our site, such as Degradation of AXIN,Disease,Diseases of signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNKS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Disease | MTRR,CCDC167,GPC5,CTBP2,SUPT5H,RBP1,KPNA5,gag,BANF1,ELL |
| Signal Transduction | LINGO1,ARHGEF17,CDC42EP1B,RGS21,TAGAP,PTPRUB,ARHGAP26,CHRDL1,C,ARAP1 |
| Diseases of signal transduction | LRRFIP1,RBP4,CTBP1,JAG2,TRIM24,HEY2,OPN1MW2,RBP1,TRAT1,DERL2 |
| TCF dependent signaling in response to WNT | PYGO2,WNT8-2,LGR4,RSPO1,RNF43,SOX9B,PYGO1,ASH2L,SRY,SOX4B |
| Signaling by WNT in cancer | TNKS,KREMEN2,RNF43,KREMEN1 |
| Signaling by Wnt | PYGO2,ROR1,SOX32,KLHL12,GPR177,LGR5,RBBP5,PRICKLE1B,FMNL3,TNKS |
| Degradation of AXIN | RNF146,TNKS |
Protein Function
TNKS2 has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity,enzyme binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNKS2 itself. We selected most functions TNKS2 had, and list some proteins which have the same functions with TNKS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme binding | ZFP36,MST1R,KMT2E,HIST1H2AD,PLSCR1,NPC2,BIRC5,PPP1R3B,WWOX,HMGA1-RS1 |
| protein binding | NPRL2,DNAJB2,CBL,RUVBL2,VAPB,GLDN,MXI1,cgr2b,SLC2A1,PCNP |
| NAD+ ADP-ribosyltransferase activity | GIG2J,PARP14,PARP3,CHAT2,PARP2,SIRT4,GIG2G,ZC3HAV1,PARP16,GIG2E |
| metal ion binding | IGFBP3,NT5C2A,ZNF606,FTH1A,ASXL1,ZSCAN18,IDO2,TRIM35-30,ZBTB8B,ERI3 |
Interacting Protein
TNKS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNKS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNKS2.
Sh3bp2;SH3BP2;BCR;RAD54L;BABAM1
Resources
Related Services
Related Products
References
