TJAP1
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Official Full Name
tight junction associated protein 1 (peripheral) -
Overview
This gene encodes a tight junction-associated protein. Incorporation of the encoded protein into tight junctions occurs at a late stage of formation of the junctions. The encoded protein localizes to the Golgi and may function in vesicle trafficking. Alternatively spliced transcript variants have been described. A related pseudogene exists on the X chromosome. -
Synonyms
TJAP1;tight junction associated protein 1 (peripheral);tight junction protein 4 (peripheral) , TJP4;tight junction-associated protein 1;PILT;tight junction protein 4 (peripheral);protein incorporated later into tight junctions;TJP4;DKFZp686F06131
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TJAP1-3245H | Recombinant Human TJAP1, GST-tagged | E.coli | Human | GST | 1-351aa | |
| TJAP1-1056HCL | Recombinant Human TJAP1 293 Cell Lysate | HEK293 | Human | Non |
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| TJAP1-416H | Recombinant Human TJAP1 Protein, His-tagged | E.coli | Human | His | Ala4-Gly272 |
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| Tjap1-417M | Recombinant Mouse Tjap1 Protein, His-tagged | E.coli | Mouse | His | Glu20-Met258 |
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| Tjap1-418R | Recombinant Rat Tjap1 Protein, His-tagged | E.coli | Rat | His | Met1-Ala225 |
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Involved Pathway
TJAP1 involved in several pathways and played different roles in them. We selected most pathways TJAP1 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TJAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | CLDN5A,RHOA,MAGI3,VAPAL,CRB3A,SRC,LLGL1,CSDA,EPB41L3B,CLDND |
Protein Function
TJAP1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TJAP1 itself. We selected most functions TJAP1 had, and list some proteins which have the same functions with TJAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | VHL,ABI1,ANK1,C12orf68,MUC7,LAT,NPEPL1,AK3,SOX17,PPFIA2 |
Interacting Protein
TJAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TJAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TJAP1.
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References
- Buckley, MM; O'Halloran, KD; et al. Modulation of enteric neurons by interleukin-6 and corticotropin-releasing factor contributes to visceral hypersensitivity and altered colonic motility in a rat model of irritable bowel syndrome. JOURNAL OF PHYSIOLOGY-LONDON 592:5235-5250(2014).
- Thway, K; Fisher, C; et al. Claudin-1 is expressed in perineurioma-like low-grade fibromyxoid sarcoma. HUMAN PATHOLOGY 40:1586-1590(2009).
