TIAL1
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Official Full Name
TIA1 cytotoxic granule-associated RNA binding protein-like 1 -
Overview
TIAR is a member of the RNA-recognition motif (RRM) family of RNA-binding proteins. It functions as a translational repressor under conditions of cellular damage. In response to cellular stress, TIAR associates with eIF1, eIF3, and the 40S ribosomal subun -
Synonyms
TIAL1;TIA1 cytotoxic granule-associated RNA binding protein-like 1;TIA1 cytotoxic granule associated RNA binding protein like 1;nucleolysin TIAR;TIAR;T-cluster binding protein;TIA-1-related nucleolysin;aging-associated gene 7 protein;TCBP;MGC3340
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TIAL1-11353Z | Recombinant Zebrafish TIAL1 | Mammalian Cells | Zebrafish | His |
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| TIAL1-16769M | Recombinant Mouse TIAL1 Protein | Mammalian Cells | Mouse | His |
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| TIAL1-599H | Recombinant Human TIAL1 Protein, His-tagged | E.coli | Human | His |
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| TIAL1-644H | Recombinant Human TIAL1 | Mammalian Cells | Human | His |
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| TIAL1-683H | Recombinant Human TIA1 cytotoxic granule-associated RNA binding protein-like 1, His-tagged | E.coli | Human | His | 1-375 a.a. |
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| TIAL1-1779HCL | Recombinant Human TIAL1 cell lysate | Human | Non |
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| TIAL1-4188H | Recombinant Human TIAL1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| TIAL1-4188H-B | Recombinant Human TIAL1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| TIAL1-9205M | Recombinant Mouse TIAL1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TIAL1-9205M-B | Recombinant Mouse TIAL1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TIAL1 involved in several pathways and played different roles in them. We selected most pathways TIAL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TIAL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TIAL1 has several biochemical functions, for example, AU-rich element binding,RNA binding,nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TIAL1 itself. We selected most functions TIAL1 had, and list some proteins which have the same functions with TIAL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | NOM1,C1orf35,PEG10,EBI3,DHX57,RPL27A,ZFR,IMMT,DIEXF,DUSP11 |
| nucleotide binding | PAK2B,PUF60A,U2SURP,RALYL,ATAD5B,RAB7,POLDIP3,MYO7A,SEPT5B,VPRBP |
| RNA binding | FAM120A,SRSF3,RBM4,SRSF12,RPL38,HNRPL,LOC81691,U2SURP,ADAD2,APOBEC3F |
| AU-rich element binding | APOBEC1,NUDT21,EXOSC9,ELAVL1,CPSF5,ZFP36L3,HNRNPA0,EXOSC7,ZFP36L1,TIA1 |
Interacting Protein
TIAL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TIAL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TIAL1.
SMN1;hmsS;BNLF1;SF1;q7cig0_yerpe;q7cjv9_yerpe;q81kr5_bacan;hmsH;ssrna_ug
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References
- Heck, MV; Azizov, M; et al. Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue. NEUROGENETICS 15:135-144(2014).
- Carrascoso, I; Sanchez-Jimenez, C; et al. Long-term reduction of T-cell intracellular antigens leads to increased beta-actin expression. MOLECULAR CANCER 13:-(2014).
