THRSP
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Official Full Name
thyroid hormone responsive -
Overview
The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipoc -
Synonyms
THRSP;thyroid hormone responsive;lipogenic protein 1 , LPGP1, thyroid hormone responsive SPOT14 (rat) homolog;thyroid hormone-inducible hepatic protein;Lpgp;S14;SPOT14;SPOT14 homolog (rat);SPOT14 homolog;spot 14 protein;lipogenic protein 1;thy
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- His&T7
- His&SUMO
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| THRSP-3223H | Recombinant Human THRSP, GST-tagged | E.coli | Human | GST | 1-146aa | |
| THRSP-7130C | Recombinant Chicken THRSP | Mammalian Cell | Chicken | His |
|
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| THRSP-7616H | Recombinant Human THRSP, His-tagged | E.coli | Human | Non | 1-146aa |
|
| THRSP-8073H | Recombinant Human THRSP protein, His & T7-tagged | E.coli | Human | His&T7 | Met1~Trp146 |
|
| THRSP-1087HCL | Recombinant Human THRSP 293 Cell Lysate | HEK293 | Human | Non |
|
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| THRSP-1929M | Recombinant Mouse THRSP Protein (1-150 aa), His-SUMO-tagged | E.coli | Mouse | His&SUMO | 1-150 aa |
|
| Thrsp-6421M | Recombinant Mouse Thrsp Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
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| THRSP-879H | Recombinant Human THRSP Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
Involved Pathway
THRSP involved in several pathways and played different roles in them. We selected most pathways THRSP participated on our site, such as Cell Cycle,Cell Cycle Checkpoints,DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with THRSP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) | RAD9B,UIMC1,HUS1,RTEL1,GEN1,PPP4CB,RNF168,BABAM1,RBBP8,RAD51AP1 |
| Cell cycle | RANGAP1B,CEP152,YWHAE1,CLSPN,FAM175A,POT1A,NCAPD2,UIMC1,CDC26,KIF2C |
| DNA Repair | PARP1,YY1,APITD1,COPS8,COPS5,DNA2,PPIE,RAD9,ACTR5,PPP4CB |
| DNA Double-Strand Break Repair | UIMC1,RTEL1,HTATIP,KDM4B,BABAM1,RAD50,EYA3,EME2,PPP4R2B,CLSPN |
| G2/M DNA damage checkpoint | BRCC3,TP53BP1,RNF168,BARD1,FAM175A,BABAM1,UIMC1,BRE |
| DNA Double Strand Break Response | SMARCA5,BRCC3,UIMC1,EYA3,KDM4B,FAM175A,KDM4A,RAD50,TP53BP1,BABAM1 |
| Cell Cycle Checkpoints | MCM10,DBF4,BRCC3,UBE2V2,RAD9B,RAD17,CDK2,BARD1,RNF168,TP53BP1 |
| G2/M Checkpoints | RAD9B,RAD1,BRCC3,HUS1,RNF168,BABAM1,BARD1,RAD9A,FAM175A,BRE |
Protein Function
THRSP has several biochemical functions, for example, polyubiquitin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by THRSP itself. We selected most functions THRSP had, and list some proteins which have the same functions with THRSP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| polyubiquitin binding | RAD18,AGL,SHARPIN,DNAJB2,RAD23B,HDAC6,UBQLN4,PSMD4,PSMD4B,TNIP3 |
Interacting Protein
THRSP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with THRSP here. Most of them are supplied by our site. Hope this information will be useful for your research of THRSP.
Plagl1;AURKA;GAMMAHV.ORF33;HMMR;BCAR3;BAG4;KRAS;TGFB1;ERBB2;IGF1R;PARP1;CDH1;PTPN1;WT1;FGFR4;AKT1;LSP1;PIK3CA;SMAD4;STK11
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References
- Hilberath, JM; Schmidt, H; et al. Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT): case report of reversible coma and status epilepticus in an adolescent patient and review of the literature. EUROPEAN JOURNAL OF PEDIATRICS 173:1263-1273(2014).
- Patnaik, SK; Upreti, V; et al. Steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT) in childhood. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 27:737-744(2014).
