TGM3
-
Official Full Name
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) -
Overview
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. -
Synonyms
TGM3;transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase);protein-glutamine gamma-glutamyltransferase E;TGE;TG(E);TGase E;TGase-3;transglutaminase E;transglutaminase-3;MGC126249;MGC126250
Recombinant Proteins
- Human
- Mouse
- Rat
- Insect Cells
- E.coli
- Sf21 Insect Cell
- Mammalian Cell
- Insect Cell
- HEK293T
- HEK293
- His
- GST
- His&S
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
TGM3 involved in several pathways and played different roles in them. We selected most pathways TGM3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TGM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TGM3 has several biochemical functions, for example, calcium ion binding,catalytic activity,protein-glutamine gamma-glutamyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TGM3 itself. We selected most functions TGM3 had, and list some proteins which have the same functions with TGM3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | RYR2,PLA2G10,F7I,EPDL1,PCDH2G28,ANXA7,PLCG1,CDH10,ANXA3,VIL1 |
| protein-glutamine gamma-glutamyltransferase activity | F13A1B,EPB42,F13A1,TGM1,EPB4.2,F13A1A.1,TGM1L4,TGM2B,TGM4,TGM2 |
| transferase activity, transferring acyl groups | NAT15,DGAT2L6,LYCAT,NAT14,Nat3,TGM2B,ZDHHC18,CRATB,PDHX,ZDHHC24 |
| catalytic activity | PGAM1,GLA,SLC3A2A,ACSS2L,AGXTA,DIP2A,PPM1LB,SCP2A,ISOC2B,PCXA |
Interacting Protein
TGM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TGM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TGM3.
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