Tet1
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Official Full Name
tet methylcytosine dioxygenase 1 -
Synonyms
TET1;tet methylcytosine dioxygenase 1;ENSMUSG00000047146;LCX;Cxxc6;AA517754;BB001228;mKIAA1676;D10Ertd17e;2510010B09Rik;10 B4;10 32.0 cM;methylcytosine dioxygenase TET1;methylcytosine dioxygenase TET1;CXXC finger 6;tet oncogene 1;CXXC-type zinc finger protein 6;ten-eleven translocation 1 gene protein homolog;EC 1.14.11.n2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TET1-2207H | Recombinant Human TET1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| TET1-235H | Recombinant Human TET1, GST-tagged | Sf9 Cells | Human | GST | 1598-end a.a. |
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| TET1-997H | Active Recombinant Human TET1, Flag-tagged | Sf9 Cells | Human | Flag | 1418-2136 a.a. |
|
Involved Pathway
Tet1 involved in several pathways and played different roles in them. We selected most pathways Tet1 participated on our site, such as Epigenetic regulation of gene expression,Gene Expression,TET1,2,3 and TDG demethylate DNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with Tet1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Epigenetic regulation of gene expression | TAF1C,SUDS3,SAP30,TET3,SAP130,SUZ12A,SIN3B,AEBP2,H3F3D,JARID2 |
| Gene Expression | SAP18,ADAT1,ZNF180,FKBP6,ZNF566,GM3258,PHF1,ZNF658,NR2F1,ZNF558 |
| TET1,2,3 and TDG demethylate DNA | TET2,TET3 |
Protein Function
Tet1 has several biochemical functions, for example, iron ion binding,methylcytosine dioxygenase activity,structure-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Tet1 itself. We selected most functions Tet1 had, and list some proteins which have the same functions with Tet1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| methylcytosine dioxygenase activity | TET3,TET2,ALKBH1 |
| zinc ion binding | XAF1,SRSF7B,PXN,RNFT2,GATA6,NR1D2B,TRIM54,ADAMTSL5,CSRP1,PIAS4A |
| iron ion binding | BBOX1,CYP2AD6,CYP4B1,HBB,CYP2P10,CYP39A1,CYP2AA1,TYW1,XDH,HBBE1.1 |
| structure-specific DNA binding | SETMAR,ENDOV,TDG,EXO1 |
Interacting Protein
Tet1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Tet1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Tet1.
OGT;SIN3A
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References
- Qu, YP; Yang, Q; et al. A Strategy for Accurate Quantification of 5-Methylcytosine and 5-Hydroxymethylcytosine at CpG Sites Within Gene Promoter. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 11:1016-1026(2015).
- Tajbakhsh, J; Stefartovski, D; et al. Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis. EXPERIMENTAL CELL RESEARCH 332:190-201(2015).
