TBL3
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Official Full Name
transducin (beta)-like 3 -
Overview
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. -
Synonyms
TBL3;transducin (beta)-like 3;transducin beta-like protein 3;SAZD;UTP13;WD-repeat protein SAZD;WD repeat-containing protein SAZD
Recombinant Proteins
- Chicken
- Mouse
- Zebrafish
- Rat
- Human
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TBL3-1317C | Recombinant Chicken TBL3 | Mammalian Cells | Chicken | His |
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| TBL3-16516M | Recombinant Mouse TBL3 Protein | Mammalian Cells | Mouse | His |
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| TBL3-1786Z | Recombinant Zebrafish TBL3 | Mammalian Cells | Zebrafish | His |
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| TBL3-5971R | Recombinant Rat TBL3 Protein | Mammalian Cells | Rat | His |
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| TBL3-1211HCL | Recombinant Human TBL3 293 Cell Lysate | HEK293 | Human | Non |
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| TBL3-5630R | Recombinant Rat TBL3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| TBL3-5630R-B | Recombinant Rat TBL3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| TBL3-9050M | Recombinant Mouse TBL3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TBL3-9050M-B | Recombinant Mouse TBL3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TBL3 involved in several pathways and played different roles in them. We selected most pathways TBL3 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | NOL6,POP7,NXF2,NMD3,GNL3,FBL,NHP2,NHP2L1B,EMG1,cka2 |
Protein Function
TBL3 has several biochemical functions, for example, poly(A) RNA binding,protein binding,snoRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBL3 itself. We selected most functions TBL3 had, and list some proteins which have the same functions with TBL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| snoRNA binding | IMP4,UTP15,NUDT7,UTP6,NOP56,NUDT4,NUDT5,NUDT1,NOP14,NUDT16 |
| poly(A) RNA binding | TBL2,MRPL11,DIMT1,NGRN,RC3H2,TSFM,WDR6,EIF4E,SF3A1,KPNA2 |
| protein binding | RALY,UBL4B,LETM1,SFTPC,KHDC3,Aatk,KIF20A,G3BP2,PROC,OSBPL6 |
Interacting Protein
TBL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBL3.
APPBP2;DHX30;NR2E3;RBBP7;USP36;NUDC;CACNB4;SFN;USP11;AURKB;URM1
Resources
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References
- Li, JW; Wang, J; et al. Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO JOURNAL 19:4342-4350(2000).
- Huang, LQ; Shanker, YG; et al. G gamma 13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. NATURE NEUROSCIENCE 2:1055-1062(1999).
