TBCC

  • Official Full Name

    tubulin folding cofactor C

  • Overview

    Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

  • Synonyms

    TBCC;tubulin folding cofactor C;tubulin specific chaperone c;tubulin-specific chaperone C;CFC;Beta tubulin cofactor C;tubulin-folding cofactor C

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
TBCC-3862H Recombinant Human TBCC protein, His-tagged E.coli Human His 1-346 aa
TBCC-16505M Recombinant Mouse TBCC Protein Mammalian Cells Mouse His
TBCC-29834TH Recombinant Human TBCC Wheat Germ Human Non 346 amino acids
TBCC-8142Z Recombinant Zebrafish TBCC Mammalian Cells Zebrafish His
TBCC-1218HCL Recombinant Human TBCC 293 Cell Lysate HEK293 Human Non
TBCC-518HF Recombinant Full Length Human TBCC Protein In Vitro Cell Free System Human Full L. 346 amino acids
Tbcc-6312M Recombinant Mouse Tbcc Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK
TBCC-825H Recombinant Human TBCC Protein (2-345 aa), His-tagged E.coli Human His 2-345 aa
TBCC-9043M Recombinant Mouse TBCC Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
TBCC-9043M-B Recombinant Mouse TBCC Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    TBCC involved in several pathways and played different roles in them. We selected most pathways TBCC participated on our site, such as Metabolism of proteins,Post-chaperonin tubulin folding pathway,Protein folding, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBCC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Post-chaperonin tubulin folding pathway TBCB,TBCE,SERPINA7,ARL2,TBCA,TBCD
    Protein folding KIFC3,PFDN5,FBXW2,ARL2,FBXW5,NOP56,PFDN6,TBCA,TBCB,CCT7
    Metabolism of proteins CNIH,GZMH,RHBDL1,PFDN6,TRAPPC4,MTX2,NSMCE4A,HDGF,SPCS3,PHC1

    Protein Function

    TBCC has several biochemical functions, for example, GTPase activity,chaperone binding,tubulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBCC itself. We selected most functions TBCC had, and list some proteins which have the same functions with TBCC. You can find most of the proteins on our site.

    Function Related Protein
    tubulin binding TBCA,PARK2,STMN3,AGBL1,NCALD,IFT81,ATF5,TTLL6,CDK5RAP2,TPPP3
    chaperone binding GRPEL1,TIMM10,GET4,DNAJB2,UBL4A,DNAJB7,DLST,CALR,TBCE,VWF
    GTPase activity EIF5B,HRAS,MTIF2,ARL4C,RAB4B,RHOG,DNAJC27,GNAI3,RHOF,RND1

    Interacting Protein

    TBCC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBCC here. Most of them are supplied by our site. Hope this information will be useful for your research of TBCC.

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