TAS1R3
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Official Full Name
taste receptor, type 1, member 3 -
Overview
The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001 -
Synonyms
TAS1R3;taste receptor, type 1, member 3;taste receptor type 1 member 3;T1R3;G protein coupled receptor;Sac;Saccharin preference;Sweet taste receptor T1R3;T1 R3;T1R 3;TAS1 R3;TAS1R 3;Taste receptor type 1 member 3 precursor;TR 3;TR3;TS1R3_HUMAN
Recombinant Proteins
- Human
- Zebrafish
- Rat
- E.coli
- HEK293
- Mammalian Cells
- His
- DDK
- Myc
- Non
- Avi
- Fc
Involved Pathway
TAS1R3 involved in several pathways and played different roles in them. We selected most pathways TAS1R3 participated on our site, such as Taste transduction,Carbohydrate digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS1R3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Taste transduction | PRKACA,TAS2R143,PDE1A,TAS2R144,TAS2R103,GNG13,TAS2R136,ITPR3,TAS2R20,TAS2R108 |
| Carbohydrate digestion and absorption | AMY2A3,HK3,HK2,GNAT3,AMY2B,AMY2A2,ATP1A3,AMY2A4,ATP1B2,PIK3R2 |
Protein Function
TAS1R3 has several biochemical functions, for example, protein heterodimerization activity,contributes_to sweet taste receptor activity,taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAS1R3 itself. We selected most functions TAS1R3 had, and list some proteins which have the same functions with TAS1R3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| taste receptor activity | TAS2R139,TAS2R13,TAS1R1,TAS2R108,TAS2R138,TAS2R137,TAS1R2,O3far1,TAS2R136,TAS2R3 |
| protein heterodimerization activity | JAM2A,SCGB2A1,KCNH5,SNX1,H2-AA,SMAD1,HIST1H2B5,ABCG1,TCF4,DLG4B |
| contributes_to taste receptor activity | TAS1R2 |
| contributes_to sweet taste receptor activity | TAS1R2 |
Interacting Protein
TAS1R3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS1R3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS1R3.
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References
- Yasumatsu, K; Manabe, T; et al. Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice. JOURNAL OF PHYSIOLOGY-LONDON 593:1021-1034(2015).
