TAS1R1
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Official Full Name
taste receptor, type 1, member 1 -
Overview
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
TAS1R1;taste receptor, type 1, member 1;G protein coupled receptor 70 , GPR70;taste receptor type 1 member 1;T1R1;TR1;G protein coupled receptor 70;gm 148;gm148;GPR 70;GPR70;Krueppel related zinc finger protein 3 (HKR3 protein);Sweet taste receptor T1r;TAS1 R1;TR 1;G protein-coupled receptor 70;G-protein coupled receptor 70;seven transmembrane helix receptor
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- N-His&C-Myc
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TAS1R1-2862H | Recombinant Human TAS1R1 protein, His-tagged | E.coli | Human | His | 22-167 aa | |
| TAS1R1-3622Z | Recombinant Zebrafish TAS1R1 | Mammalian Cell | Zebrafish | His |
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| TAS1R1-5931R | Recombinant Rat TAS1R1 Protein | Mammalian Cell | Rat | His |
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| TAS1R1-1249HCL | Recombinant Human TAS1R1 293 Cell Lysate | HEK293 | Human | Non |
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| TAS1R1-1956H | Recombinant Human TAS1R1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Tas1r1-2114M | Recombinant Mouse Tas1r1 Protein, His-tagged | E.coli | Mouse | His | Trp20-Gln258 |
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| TAS1R1-2435H | Recombinant Human TAS1R1 protein, His&Myc-tagged | E.coli | Human | N-His&C-Myc | 21-567aa |
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| Tas1r1-465M | Recombinant Mouse Tas1r1 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| TAS1R1-5590R | Recombinant Rat TAS1R1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| TAS1R1-5590R-B | Recombinant Rat TAS1R1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
TAS1R1 involved in several pathways and played different roles in them. We selected most pathways TAS1R1 participated on our site, such as Taste transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS1R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Taste transduction | ITPR3,Adcy4,TAS2R108,TAS2R136,TAS1R3,TAS2R137,TRPM5,KCNB1,TAS2R109,TAS2R116 |
Protein Function
TAS1R1 has several biochemical functions, for example, protein heterodimerization activity,taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAS1R1 itself. We selected most functions TAS1R1 had, and list some proteins which have the same functions with TAS1R1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| taste receptor activity | TAS2R108,TAS2R139,TAS2R138,TAS2R136,TAS1R2,GPR120,TAS2R134,TAS2R140,TAS2R3,TAS2R13 |
| protein heterodimerization activity | PANX1,EGFR,MAFGB,SMAD4,OSTA,NR4A2,PRMT8,VAPA,HIST1H2BN,RRAGC |
Interacting Protein
TAS1R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS1R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS1R1.
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References
- Tornwall, O; Silventoinen, K; et al. Identifying flavor preference subgroups. Genetic basis and related eating behavior traits. APPETITE 75:1-10(2014).
- Liu, GJ; Walter, L; et al. Differentiated adaptive evolution, episodic relaxation of selective constraints, and pseudogenization of umami and sweet taste genes TAS1Rs in catarrhine primates. FRONTIERS IN ZOOLOGY 11:-(2014).
