TARS2
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Official Full Name
threonyl-tRNA synthetase 2, mitochondrial (putative) -
Synonyms
TARS2;threonyl-tRNA synthetase 2, mitochondrial (putative);TARSL1, threonyl tRNA synthetase like 1;threonyl-tRNA synthetase, mitochondrial;FLJ12528;threonine tRNA ligase 2;mitochondrial;Threonine tRNA ligase;ThrRS;TARS 2;TARSL1;Threonyl tRNA synthetase 2, mitochondrial;Threonyl tRNA synthetase like 1;threonine--tRNA ligase;threonyl-tRNA synthetase-like 1;threonine tRNA ligase 2, mitochondrial
Recombinant Proteins
- Mouse
- Human
- Rat
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
- His&SUMO
Involved Pathway
TARS2 involved in several pathways and played different roles in them. We selected most pathways TARS2 participated on our site, such as Aminoacyl-tRNA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TARS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aminoacyl-tRNA biosynthesis | PSTK,LARS2,SEPSECS,GATC,DARS2,QRSL1,YARS,IARS2,KARS,TARSL2 |
Protein Function
TARS2 has several biochemical functions, for example, ATP binding,molecular_function,threonine-tRNA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TARS2 itself. We selected most functions TARS2 had, and list some proteins which have the same functions with TARS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | DDX46,ATP2B2,UBE2E2,MYH6,HELB,PIP5K2,EPHA5,ABCC1,POMK,DARS2 |
| molecular_function | APOL4,NOG3,TTC39A,TMEM198B,LIPN,EML5,RER1,NLRP4E,FAM149B,C2orf49 |
| threonine-tRNA ligase activity | TARSL2,TARS |
Interacting Protein
TARS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TARS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TARS2.
EIF4A2;ssrna_ug;AHSA1;ICT1;CDC37;P;Mad2l2;CHORDC1;FKBPL
Resources
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References
- Diodato, D; Melchionda, L; et al. VARS2 and TARS2 Mutations in Patients with Mitochondrial Encephalomyopathies. HUMAN MUTATION 35:983-989(2014).
- Genini, S; Zangerl, B; et al. Transcriptional Profile Analysis of RPGRORF15 Frameshift Mutation Identifies Novel Genes Associated with Retinal Degeneration. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 51:6038-6050(2010).
