TARS
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Official Full Name
threonyl-tRNA synthetase -
Overview
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family -
Synonyms
TARS;threonyl-tRNA synthetase;threonine--tRNA ligase, cytoplasmic;threonine tRNA ligase 1;cytoplasmic;threonine tRNA ligase 1, cytoplasmic;threonyl-tRNA synthetase, cytoplasmic;ThrRS;MGC9344
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- Zebrafish
- E.coli
- Mammalian Cells
- Sf9 Cells
- HEK293
- His
- His&Fc&Avi
Involved Pathway
TARS involved in several pathways and played different roles in them. We selected most pathways TARS participated on our site, such as Aminoacyl-tRNA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TARS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aminoacyl-tRNA biosynthesis | WARS2,MARS,MADD,GATC,YARS2,YARS,DARS2,PARS2,WARS,IARS2 |
Protein Function
TARS has several biochemical functions, for example, ATP binding,protein binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TARS itself. We selected most functions TARS had, and list some proteins which have the same functions with TARS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | EVLA,DGCR8,CHMP1A,DMRTB1,BARD1,CBX5,CTBP2,AMBP,SPATA24,HIF1AN |
| threonine-tRNA ligase activity | TARSL2,TARS2 |
| ATP binding | MYHZ1.1,NTRK3A,PLK4,ROS1,ACVR1BA,RPS6KA5,DHX57,CLK2,PL10,HSPE1 |
| protein binding | NFKBIA,TCEA2,ATCAY,C1S,TNNI3K,SELS,TRAF3IP3,IMPDH2,MID2,MTMR6 |
Interacting Protein
TARS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TARS here. Most of them are supplied by our site. Hope this information will be useful for your research of TARS.
TARSL2;C7orf25;VCAM1;gag;PIK3C2A;GBAS;BCAR3;MCC;HLA-B;VHL;PRKAG1;ARF6
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References
- de Mendoza, C; Barreiro, P; et al. Gene therapy for HIV infection. EXPERT OPINION ON BIOLOGICAL THERAPY 15:319-327(2015).
- Sobhanifar, S; Worrall, LJ; et al. Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E576-E585(2015).
