TAGLN
-
Official Full Name
transgelin -
Overview
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. -
Synonyms
TAGLN;transgelin;DKFZp686P11128;SM22;SM22 alpha;SMCC;TAGLN1;transgelin variant 2;WS3 10;22 kDa actin binding protein;22 kDa actin-binding protein;Human 22kDa smooth muscle protein;Protein WS3-10;SM22-alpha;Smooth muscle protein 22-alpha;TAGL_HUMAN;OTTHUMP00000234990;OTTHUMP00000234991;OTTHUMP00000234992;OTTHUMP00000234994;OTTHUMP00000234995;OTTHUMP00000234996;WS3-10
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- Zebrafish
- Rat
- Chicken
- E. coli
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Mamanlian cells
- His
- GST
- Myc&DDK
- His&T7
- Non
- His&Fc&Avi
- Flag
Involved Pathway
TAGLN involved in several pathways and played different roles in them. We selected most pathways TAGLN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TAGLN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TAGLN has several biochemical functions, for example, actin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAGLN itself. We selected most functions TAGLN had, and list some proteins which have the same functions with TAGLN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | CAPG,RP2,MYH1E,MYLK,MYOT,SMTNL,SNTB1,CCDC88A,CAPZA1,SPTBN2 |
| protein binding | ROBO2,MKI67IP,TGFBR1,NPHP4,GADD45G,CASP9,GSK3B,DRAXIN,RPUSD3,ACSF2 |
Interacting Protein
TAGLN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAGLN here. Most of them are supplied by our site. Hope this information will be useful for your research of TAGLN.
TINF2;GIPC1;AGR2;S100A9;IGF1R;CFL1;MLH1;ACD;POT1
Resources
Research Area
Cardiac Stem Cell MarkersMyogenesis Markers
Smooth Muscle Cell Markers
Invadopodia Molecules
Related Services
Related Products
References
