TAF7
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Official Full Name
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -
Overview
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. -
Synonyms
TAF7;TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa;TAF2F, TATA box binding protein (TBP) associated factor, RNA polymerase II, F, 55kD;transcription initiation factor TFIID subunit 7;TAFII55;TAFII-55;TAF(II)55;TBP
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Chicken
- Zebrafish
- Cynomolgus
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- His&MBP
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
TAF7 involved in several pathways and played different roles in them. We selected most pathways TAF7 participated on our site, such as Basal transcription factors, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basal transcription factors | TBPL1,GTF2H2C_2,TAF9B,GTF2A1,TBP,TAF11,GTF2H2C,TAF1,TAF9,GTF2F2 |
Protein Function
TAF7 has several biochemical functions, for example, histone acetyltransferase binding,protein binding,thyroid hormone receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF7 itself. We selected most functions TAF7 had, and list some proteins which have the same functions with TAF7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| histone acetyltransferase binding | TP53,EID1,CITED2,MEF2A,TRP53,ZBTB7A,PCNA,MYOCD,CEBPB,SIRT2 |
| vitamin D receptor binding | THRAP3,MED16,RXRA,TAF11,MED14,MED1,RUNX2B,MED24,MED17,MED30 |
| contributes_to transcription factor activity, sequence-specific DNA binding | SOX1B,MAFGA,SOX1A,NFE2L2A,TRIM28,SOX19B,SMAD3,TAF12,TAF10,SMAD2 |
| transcription factor binding | SRF,HOXA7,TWIST1,PIK3R1,PRICKLE1,KAT6B,BRD7,APBB2,NLRP3,SOX10 |
| transcription regulatory region DNA binding | SREBF1,HOXA13,TCF7L2,FOXM1,SOX17,BCL11AA,TCF7L1B,PRDM5,CDK5RAP2,TCF7L1A |
| thyroid hormone receptor binding | NCOA3,MED12,NCOR1,MED4,THRAP3,NUP62,TRIP12,NR0B2,MED16,FUS |
| protein binding | MRPL53,STXBP4,THAP7,CHD4,ITGB1BP2,MED9,RAD21,CYLD,GDAP2,DYNLRB1 |
| transcription coactivator activity | MED27,DYRK1B,KAT2B,RNF4,SIX3,MED23,GATA3,RB1,MED26,ZSCAN1 |
Interacting Protein
TAF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF7.
FAU;RBM6;q81ws0_bacan;MAP1LC3B;h3_peptide_2-18;MED26;TBP;CCNA2;CDK2;SNCA;WDR5;TAF10;Smad3;KIFAP3;Ndc80
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