TAF5L
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Official Full Name
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -
Overview
The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. -
Synonyms
TAF5L;TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa;TAF5 like RNA polymerase II, p300/CBP associated factor (PCAF) associated factor, 65 kD;TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L;PAF65B;PCAF associated factor 65 beta;1110005N04Rik;AI849020;OTTHUMP00000037470;OTTHUMP00000037471;PAF65 beta;PAF65-beta;PCAF-associated factor 65 beta;TAF 5L;TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor 65 kD;TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor 65 kDa;TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor;TAF5 like RNA polymerase II p300/CBP associated factor associated factor 65 kDa subunit 5L;TAF5 like RNA polymerase II p300/CBP associated factor associated factor 65kDa;Taf5l protein;TAF5L_HUMAN
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TAF5L-3105H | Recombinant Human TAF5L, His-tagged | E.coli | Human | His | 1-325aa | |
| TAF5L-10225Z | Recombinant Zebrafish TAF5L | Mammalian Cell | Zebrafish | His |
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| TAF5L-16398M | Recombinant Mouse TAF5L Protein | Mammalian Cell | Mouse | His |
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| TAF5L-30936TH | Recombinant Human TAF5L, His-tagged | E.coli | Human | His | 349-589 a.a. |
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| TAF5L-4609R | Recombinant Rhesus monkey TAF5L Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| TAF5L-1268HCL | Recombinant Human TAF5L 293 Cell Lysate | HEK293 | Human | Non |
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| TAF5L-3549H | Recombinant Human TAF5L protein, GST-tagged | E.coli | Human | GST | 1-325aa |
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| TAF5L-4425R | Recombinant Rhesus Macaque TAF5L Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| TAF5L-4425R-B | Recombinant Rhesus Macaque TAF5L Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| TAF5L-8969M | Recombinant Mouse TAF5L Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TAF5L-8969M-B | Recombinant Mouse TAF5L Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TAF5L involved in several pathways and played different roles in them. We selected most pathways TAF5L participated on our site, such as Basal transcription factors,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF5L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Herpes simplex infection | TP53,CDC34,IFNA2,TLR9,RNASEL,HLA-DQB1,IL12BA,EIF2AK3,IFNAR2,MAPK8 |
| Basal transcription factors | TAF6,TAF2,TAF5,CDK7,GTF2H2C_2,GTF2F2,TAF1L,GTF2A1L,TAF7,GTF2I |
Protein Function
TAF5L has several biochemical functions, for example, contributes_to histone acetyltransferase activity,transcription coactivator activity,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF5L itself. We selected most functions TAF5L had, and list some proteins which have the same functions with TAF5L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to histone acetyltransferase activity | TADA2B,TADA2A,TAF10,TADA1,TADA3,KAT5,ELP4,TAF9,ING3,TAF12 |
| transcription coactivator activity | VGLL2,JUNBB,SOX10,MAX,KDM5A,MED7,WWC1,TFAP2B,NACA,MED27 |
| transcription factor activity, sequence-specific DNA binding | TFAP2C,NFE2L1B,PPARAB,SOX11A,CSRNP1,TRIM25,HSFX1,PHTF1,NR1D2B,ZKSCAN5 |
Interacting Protein
TAF5L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF5L here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF5L.
KAT2B;USP22;TTR;H2AFX;ANXA7;CDKN1A;TSC22D1;KAT2A;CCDC101;CDC5L
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