TAF1C

  • Official Full Name

    TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa

  • Overview

    Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding;protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds;to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory;signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding;different isoforms have been identified.

  • Synonyms

    TAF1C;TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa;TATA box binding protein (TBP) associated factor, RNA polymerase I, C, 110kD;TATA box-binding protein-associated factor RNA polymerase I subunit C;MGC:39976;SL1;TAFI

Recombinant Proteins

  • Mouse
  • Human
  • Rat
  • Mammalian Cell
  • E.coli
  • HEK293
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
TAF1C-16392M Recombinant Mouse TAF1C Protein Mammalian Cell Mouse His
TAF1C-30935TH Recombinant Human TAF1C, His-tagged E.coli Human His 247-742 a.a.
TAF1C-5915R Recombinant Rat TAF1C Protein Mammalian Cell Rat His
TAF1C-1733HCL Recombinant Human TAF1C cell lysate Human Non
TAF1C-5574R Recombinant Rat TAF1C Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
TAF1C-5574R-B Recombinant Rat TAF1C Protein Pre-coupled Magnetic Beads HEK293 Rat
TAF1C-8966M Recombinant Mouse TAF1C Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
TAF1C-8966M-B Recombinant Mouse TAF1C Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    TAF1C involved in several pathways and played different roles in them. We selected most pathways TAF1C participated on our site, such as Epigenetic regulation of gene expression,Gene Expression,Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression MAEL,ZFP30,CTGF,SET,TYW1,BCAS2,NR0B2A,ZNF266,TYW5,ZNF584
    Epigenetic regulation of gene expression BAZ2A,SAP30L,CD3EAP,SUDS3,TAF1B,EFCAB11,DNMT3B,PHF19,SAP130,AEBP2
    Negative epigenetic regulation of rRNA expression RRP8,SUDS3,SAP130,CD3EAP,BAZ2A,SAP30BP,TAF1A,SAP30,EFCAB11,DNMT1
    RNA Polymerase I Chain Elongation CBX3A,CD3EAP,EFCAB11,TAF1A,UBTF,TAF1B,TAF1D,CBX3
    RNA Polymerase I Promoter Clearance CHD4A,MBD3B,MBD3,EHMT2,CHD4,UBTF,MTA3,MTA1,MTA2,MBD3A
    NoRC negatively regulates rRNA expression TAF1B,DNMT1,BAZ2A,SAP30BP,CD3EAP,TAF1A,SAP130,DNMT3B,EFCAB11,SIN3B
    RNA Polymerase I Promoter Escape RRN3,TAF1B,TAF1D,TAF1A,CD3EAP,EFCAB11,UBTF
    RNA Polymerase I Transcription TAF1A,MTA1,CBX3A,PTRF,CD3EAP,MTA3,CBX3,TAF1B,RRN3,MBD3A

    Protein Function

    TAF1C has several biochemical functions, for example, RNA polymerase I CORE element sequence-specific DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1C itself. We selected most functions TAF1C had, and list some proteins which have the same functions with TAF1C. You can find most of the proteins on our site.

    Function Related Protein
    protein binding BRD4,C20orf195,MAPK15,AP4B1,CPT1B,SLC4A4,TOB1,MED27,PRAC,EXOC1
    RNA polymerase I CORE element sequence-specific DNA binding SMARCA4,EFCAB11,BAZ2A,TAF1B,PIH1D1,RRN3,SMARCB1

    Interacting Protein

    TAF1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1C here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1C.

    TBP;SET;TAF12;TAF1B;TAF1D;TTR;TK1;H2AFX;SMN1;UFD1L

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