TAE1

  • Official Full Name

    TAE1 Tae1p [ Saccharomyces cerevisiae S288c ]

  • Overview

    Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of the ribosomal proteins RPL12A, RPL12B, RPS25A and RPS25B.

  • Synonyms

    TAE1;Tae1p;YBR261C, NTM1
Cat.# Product name Source (Host) Species Tag Protein Length Price
TAE1-7904H Recombinant Human TAE1 E.coli Human Non

    Involved Pathway

    TAE1 involved in several pathways and played different roles in them. We selected most pathways TAE1 participated on our site, such as Choline metabolism in cancer,Effects of PIP2 hydrolysis,G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerolipid metabolism ALDH3A2A,PNLIP,LIPF,AGPAT9,AGPAT2,DAK,PNPLA2,ALDH9A1A.1,CEL.1,GLA
    GPCR downstream signaling ADM2,PYY,SSTR4,RGS4,TAS2R7,NMB,MCF2L,LPAR2B,VIP2,RXFP2
    G alpha (q) signalling events NMU,TRPC6A,OPN4.1,UTS2,DGKG,KISS1,ABHD12,GPR65,LPAR5A,ANXA1C
    Glycerophospholipid metabolism CDS2,CHPT1,GPAT2,LPIN2,CHAT,ACHE,PCYT1AA,EPT1,STIL,PLA2G2A
    Gastrin-CREB signalling pathway via PKC and MAPK NPFF,ANXA1C,NTS,NPFFR2,TRIO,NMB,GPR65,ABHD12,TRH,GPR68
    Hemostasis MFN1,CAP1,CABLES2,PRTN3,CBX5,APOER2,HBG2,TRPC3,KIF22,DOCK8
    Effects of PIP2 hydrolysis MGLL,ABHD6B,DGKA,DGKQ,TRPC7,ABHD12,PRKCHB,TRPC6A,DGKG,RASGRP2
    Choline metabolism in cancer PDGFB,PIK3R1,RAC3,DGKQ,GPCPD1,MTOR,PLA2G4B,RALGDS,TSC1,PDGFD

    Protein Function

    TAE1 has several biochemical functions, for example, ATP binding,diacylglycerol kinase activity,enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAE1 itself. We selected most functions TAE1 had, and list some proteins which have the same functions with TAE1. You can find most of the proteins on our site.

    Function Related Protein
    enzyme inhibitor activity WDTC1,PLN,PRPSAP1,CALU,KIAA1967,CSN2,PPP1R12A,DGKZ,OAZ1A,ARRB1
    protein binding E2F3,EHMT1,NXT2,KCTD9,ARF5,PYY,SUB1,BABAM1,PPP1R13L,KCNRG
    lipid kinase activity DGKZ,PIK3C2B
    ATP binding IGF1RB,EPHA4,ACVR2A,CCC2,UBE2D1B,MARK1,ABCB7,P2RX1,DDX39,SMARCAL1
    protein C-terminus binding CSK,XRCC6,VIM,TAX1BP3,DLG1,CDC20,AXIN1,TRP53,ERCC3,LCK
    diacylglycerol kinase activity AGK,DGKB,DGKD,DGKAA,DGKE,DGKQ,DGKG,DGKA,DGKZ
    metal ion binding NPTXR,PAPD7,KCND3,MORC1,ZMYND17,PRUNE,ZSCAN20,RNF148,CBFA2T3,EFCAB5

    Interacting Protein

    TAE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAE1.

    ILV1;CTT1;PIS1;SNA3;CTA1;HSP26;SEC18;ycp7_yeast;RNQ1;CAT2;MAC1;nnrd_yeast;PCH2;PBP2;yhr2_yeast;phs_yeast;QNS1;UBA4;APE4;MBB1

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