TAE1

  • Official Full Name

    TAE1 Tae1p [ Saccharomyces cerevisiae S288c ]

  • Overview

    Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of the ribosomal proteins RPL12A, RPL12B, RPS25A and RPS25B.

  • Synonyms

    TAE1;Tae1p;YBR261C, NTM1
Cat.# Product name Source (Host) Species Tag Protein Length Price
TAE1-7904H Recombinant Human TAE1 E.coli Human Non

    Involved Pathway

    TAE1 involved in several pathways and played different roles in them. We selected most pathways TAE1 participated on our site, such as Choline metabolism in cancer,Effects of PIP2 hydrolysis,G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    G alpha (q) signalling events MLN,ABHD12,FPR-RS3,NMS,TAC3,CHRM5,RASGRP2,NMBA,LPAR1,NMBB
    Glycerolipid metabolism MGLL,MOGAT3A,AGPAT4,LCLAT1,MBOAT1,GPAM,Akr1b3,LPL,AKR1A1,LIPC
    GPCR downstream signaling GPR4,RGR,OR4D2,HCAR1-2,SST1.1,ADORA2B,RGS19,EDN2,ARHGEF3,GNA13
    Hemostasis KCNMA1,CD9B,KIF5A,SERPINA1L,IRF2A,KIF2A,DGKB,PROCR,CAP1,HRG
    Effects of PIP2 hydrolysis ABHD12,DGKB,DGKA,PRKCHB,DGKG,TRPC3,TRPC6A,RASGRP2,ABHD6B,DGKQ
    Glycerophospholipid metabolism PGS1,LPCAT3,DGKQ,PLA2G1B,GPD2,CDS2,LPCAT1,PLA2G12B,AGPAT6,AGPAT2
    Choline metabolism in cancer MAP2K2,SLC22A1,PLA2G4B,WASF2,SP1,WASF3,PLD1,CHKB,PLA2G4D,SLC44A1
    Gastrin-CREB signalling pathway via PKC and MAPK NPFFR2,UTS2D,NPS,GPR132B,OPN4B,LTB4R,GPR65,ABHD12,PMCH,EDN3

    Protein Function

    TAE1 has several biochemical functions, for example, ATP binding,diacylglycerol kinase activity,enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAE1 itself. We selected most functions TAE1 had, and list some proteins which have the same functions with TAE1. You can find most of the proteins on our site.

    Function Related Protein
    enzyme inhibitor activity OAZ2A,FRY,PRPSAP1,CALU,UGT1A7,OAZ1A,SCG5,PDE6G,PDE6H,TXNIP
    diacylglycerol kinase activity DGKB,DGKE,DGKG,AGK,DGKZ,DGKAA,DGKQ,DGKA,DGKD
    protein binding ABI2,MSH3,MED30,MAP1LC3C,ZNF227,CDK11B,PTPRB,ADH1A,TRPV5,ORC3L
    ATP binding DGKD,MYH13,NMRK2,ATP11C,MAP2K1,WRN,TWF1,RAD51,CLK2,PIK3C3
    lipid kinase activity PIK3C2B,DGKZ
    metal ion binding VDRA,TGM1,ZFP354A,BA1,GNAZ,ZNF643,PDE5AB,ZNF443,ZNF584,SMAD9
    protein C-terminus binding CTNNB1,VGLL3,CEP135,MIF4GD,DDX1,XRCC6,RBFOX1,AP2A1,YWHAQ,DLG1

    Interacting Protein

    TAE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAE1.

    ILV1;CTT1;PIS1;SNA3;CTA1;HSP26;SEC18;ycp7_yeast;RNQ1;CAT2;MAC1;nnrd_yeast;PCH2;PBP2;yhr2_yeast;phs_yeast;QNS1;UBA4;APE4;MBB1

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