TAE1

  • Official Full Name

    TAE1 Tae1p [ Saccharomyces cerevisiae S288c ]

  • Overview

    Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of the ribosomal proteins RPL12A, RPL12B, RPS25A and RPS25B.

  • Synonyms

    TAE1;Tae1p;YBR261C, NTM1
Cat.# Product name Source (Host) Species Tag Protein Length Price
TAE1-7904H Recombinant Human TAE1 E.coli Human Non

    Involved Pathway

    TAE1 involved in several pathways and played different roles in them. We selected most pathways TAE1 participated on our site, such as Choline metabolism in cancer,Effects of PIP2 hydrolysis,G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Choline metabolism in cancer PPAP2C,PDGFD,SLC5A7,RAC2,CHKB,DGKE,DGKG,WASF2,CHKA,PIK3CD
    Glycerophospholipid metabolism AGPAT4,AGPAT6,CHAT,LYPLA2,GPD1B,PCYT2,PTDSS2,TAZ,CEPT1,PLA2G16
    GPCR downstream signaling PTGDR2,EDN1,ARHGEF25,OXGR1A.2,CHRM2,EDN3,RAMP2,OXGR1A.1,CXCR6,LPAR1
    Gastrin-CREB signalling pathway via PKC and MAPK FPR-RS4,MLN,TRH,GCGA,OPN4,GRP,OPN4.1,DGKG,NMU,DGKB
    Hemostasis GRB7,SLC16A1,F9A,MFN2,CLU,RACGAP1,DOCK7,TRPC3,GATA5,F9B
    G alpha (q) signalling events APPA,LPAR5A,RGS18,FPR-RS3,EDNRAB,DGKG,NMBA,GPR65,TAC1,RGS19
    Effects of PIP2 hydrolysis TRPC3,DGKA,DGKQ,PRKCHB,MGLL,RASGRP2,TRPC6A,ABHD6B,ABHD12,TRPC7
    Glycerolipid metabolism MBOAT2B,MGLL,DGKB,AGK,AKR1A1A,MOGAT3,LCLAT1,AGPAT9,DAK,AKR1B1

    Protein Function

    TAE1 has several biochemical functions, for example, ATP binding,diacylglycerol kinase activity,enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAE1 itself. We selected most functions TAE1 had, and list some proteins which have the same functions with TAE1. You can find most of the proteins on our site.

    Function Related Protein
    diacylglycerol kinase activity DGKB,DGKG,DGKD,DGKE,DGKAA,DGKA,DGKZ,AGK,DGKQ
    metal ion binding ZNF729,Atp8a2,TSSK1,RBM22,ZNF136,ACVR2A,CYP2X9,Car12,PRSS37,RNF148
    lipid kinase activity PIK3C2B,DGKZ
    enzyme inhibitor activity SLN,APBA3,APOV1,SCG5,CALU,ATPIF1,PLN,GCHFR,UGT1A9,OAZ2B
    ATP binding FARSA,OXSR1A,STK19,RAF1A,CMPK2,DDR1,KIF22,CARNS1,MAP2K1,HSPD1
    protein C-terminus binding TOP2A,CITED1,ARL6IP5,SREBF2,RAD51,PPP2CA,HPCAL4,KCNK3,TRP53,MID1IP1
    protein binding LARP2,SETD7,INPP5B,PSMA4,RAB7L1,ARHGEF12,HNRPLL,Casp3,PPP1R16A,C1GALT1C1

    Interacting Protein

    TAE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAE1.

    ILV1;CTT1;PIS1;SNA3;CTA1;HSP26;SEC18;ycp7_yeast;RNQ1;CAT2;MAC1;nnrd_yeast;PCH2;PBP2;yhr2_yeast;phs_yeast;QNS1;UBA4;APE4;MBB1

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