TACR1
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Official Full Name
TACR1 tachykinin receptor 1 -
Overview
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. -
Synonyms
TACR1;tachykinin receptor 1;TAC1R;substance-P receptor;NK1R;NKIR;SPR;NK-1R;NK-1 receptor;tachykinin receptor 1 (substance P receptor;neurokinin-1 receptor)
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Chicken
- Human
- Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)
- Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)
- Mus musculus
- Dog
- Guinea pig
- Mammalian Cells
- HEK293
- E.coli
- Insect Cells
- His
- Non
- His&Flag
- GST
- His&Fc&Avi
Involved Pathway
TACR1 involved in several pathways and played different roles in them. We selected most pathways TACR1 participated on our site, such as Calcium signaling pathway,Neuroactive ligand-receptor interaction,Measles, which may be useful for your reference. Also, other proteins which involved in the same pathway with TACR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | TAAR8C,PARD3,PTGER1C,GRM7,LOC100328615,CHRNA6,PRSS1,GRM4,LPAR4,PRLR |
| Calcium signaling pathway | EDNRAA,ADORA2AB,PTGER1C,CALM2B,P2RX3,TNNC1A,GNA15,SLC8A2,HTR5A,DRD1 |
| Measles | MAVS,SH2D1A,IFNGR2,EIF2AK4,CD209A,HSPA1A,OAS2,TRP53,IFNA21,IRF3 |
Protein Function
TACR1 has several biochemical functions, for example, protein binding,substance P receptor activity,tachykinin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TACR1 itself. We selected most functions TACR1 had, and list some proteins which have the same functions with TACR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tachykinin receptor activity | TACR2,TACR3A,TACR1B,TACR3L,TACR3,TACR1A |
| substance P receptor activity | TACR1A |
| protein binding | PTPRG,CDC42BPG,KIF2C,MIA3,KPNA4,PKM,RHOBTB3,NEU4,PHF21A,PSMA2 |
Interacting Protein
TACR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TACR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TACR1.
TAC1
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