SYT11
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Official Full Name
synaptotagmin XI -
Overview
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. -
Synonyms
SYT11;synaptotagmin XI;synaptotagmin-11;DKFZp781D015;KIAA0080;MGC10881;MGC17226;synaptotagmin 12;SYT12;sytXI
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SYT11-3079H | Recombinant Human SYT11, GST-tagged | E.coli | Human | GST | C-term-273aa | |
| SYT11-16327M | Recombinant Mouse SYT11 Protein | Mammalian Cell | Mouse | His |
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| SYT11-48H | Recombinant Human SYT11 protein, His-tagged | E.coli | Human | His |
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| SYT11-1309HCL | Recombinant Human SYT11 293 Cell Lysate | HEK293 | Human | Non |
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| RFL35785RF | Recombinant Full Length Rat Synaptotagmin-11(Syt11) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-430) |
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| SYT11-8922M | Recombinant Mouse SYT11 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SYT11-8922M-B | Recombinant Mouse SYT11 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SYT11 involved in several pathways and played different roles in them. We selected most pathways SYT11 participated on our site, such as Parkinsons Disease Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYT11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Parkinsons Disease Pathway | PARK7,LRRK2,UBE2J2,ATXN2 |
Protein Function
SYT11 has several biochemical functions, for example, calcium ion binding,calcium-dependent phospholipid binding,clathrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYT11 itself. We selected most functions SYT11 had, and list some proteins which have the same functions with SYT11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | TMEM8C,PCLO,Npnt,MMP8,SYT7,PLCD1,CDH24,SYT5B,NKD1,PCDH8 |
| calcium-dependent phospholipid binding | SYT1B,PLA2G4A,C2CD4A,ANXA11A,ANXA2B,ANXA2A,CPNE1,PLA2G4B,SYT5,SYT12 |
| clathrin binding | PICALM,SYT16,SYT5,SYT7,SYT10,TOM1L1,SCLT1,SYTL4,SYT2,AFTPH |
| protein binding | DOK4,DPP3,LRRC75A-AS1,AGR3,LNPEP,IRS4,FAM64A,HPX,RIC8,AREG |
| syntaxin binding | STXBP5A,RPH3AL,SYT9,PTPN2,SNAP23,TXLNA,CPLX3A,SYTL3,STX16,DOC2D |
Interacting Protein
SYT11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYT11 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYT11.
SGTA;APPBP2;ATP13A2;CSNK1A1
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