STAMBP
-
Official Full Name
STAM binding protein -
Overview
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
STAMBP;STAM binding protein;AMSH;MICCAP;STAM-binding protein;endosome-associated ubiquitin isopeptidase;associated molecule with the SH3 domain of STAM
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- E. coli
- Sf21 Insect Cell
- Mammalian Cell
- HEK293
- HEK293T
- Insect Cell
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
STAMBP involved in several pathways and played different roles in them. We selected most pathways STAMBP participated on our site, such as Endocytosis,Internalization of ErbB1, which may be useful for your reference. Also, other proteins which involved in the same pathway with STAMBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | AP2M1B,RAB35B,IGF2R,VPS37A,GRK7,KDR,SNX1,SNX12,IGF1R,LDLRAP1A |
| Internalization of ErbB1 | FMNL3,SPRY2,ZFYVE28,RNF103-CHMP3 |
Protein Function
STAMBP has several biochemical functions, for example, metal ion binding,metallopeptidase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STAMBP itself. We selected most functions STAMBP had, and list some proteins which have the same functions with STAMBP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | EIF4EBP3,BMI1,LPXN,FAM96A,STARD13,ASIC2,E2F5,KHDC1A,C10orf137,DRG1 |
| protein domain specific binding | SKI,HIST1H4H,HIST1H4I,COX4I2,CNTROB,PPARA,ARFIP2B,ACSL3,STMN3,VCP |
| metal ion binding | PDE6B,CRYAA,PDE4B,ZNF726,ZNF606,NR5A1A,AMDHD1,ARHGEF38,PPM1NB,UBR1 |
| metallopeptidase activity | ADAM9,LNPEP,TMEM27,CLCA3,PAPPAB,ADAM10A,PAPPA2,MEP1A.2,C6AST3,ADAM25 |
| ubiquitin-specific protease activity | USP9,USP51,USP27X,USP12A,OTUB1,ATXN3,USP13,USP43,USP24,USP34 |
Interacting Protein
STAMBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAMBP here. Most of them are supplied by our site. Hope this information will be useful for your research of STAMBP.
GRB2;CHMP1B;CHMP3
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