Sstr2
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Official Full Name
somatostatin receptor 2 -
Synonyms
Somatostatin receptor type 2;SRIF-1;SRIF1;SS-2-R;SS2-R;SS2R;SSR2_HUMAN;SST2;SSTR2
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- Dog
- Sus scrofa (Pig)
- Mus musculus
- Bovine
- E.coli
- HEK293
- Mammalian Cells
- GST
- His
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
Sstr2 involved in several pathways and played different roles in them. We selected most pathways Sstr2 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with Sstr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G alpha (i) signalling events | CASR,AGT,RGS4,CCL27,TAS2R16,RGS19,ANXA1,OXGR1A.3,POMCB,APPB |
| Neuroactive ligand-receptor interaction | ADRB2A,TAAR12C,HRH2,TAAR14F,HTR1AB,GRIK3,CNR1,P2RX2,PRLHR2B,P2RX3 |
| GPCR ligand binding | CXCL11.8,PYY,CRH,PRLH,OPN1LW1,RHOL,ADRA2B,RLN3A,ADCYAP1B,OPN4.1 |
| GPCRs, Other | CELSR2,GPR55,OR10A5,GPR183,S1PR1,GPR18,VMN1R47,GPR61,VMN1R43,GPR88 |
| GPCRs, Class A Rhodopsin-like | DRD3,GPR4,GPR77,CCRL2,ADORA3,GPR85,CNR2,ADORA1,SSTR3,CNR1 |
| Class A/1 (Rhodopsin-like receptors) | PROK2,ZFPM2B,GPR68,GPR31,KISS1,CCR7,OPN1MW,AGT,PENKB,GPR120 |
| Gastric acid secretion | ATP1A3,GNAI3,ATP1A1,Adcy4,ACTB,KCNJ2,PRKACG,Slc4a2,ATP1B4,SLC9A1 |
| GPCR downstream signaling | GPRC6A,PYYA,CRHB,ABHD12,CRH,LTB4R,SST,PROK2,AMCF-II,OR52J3 |
Protein Function
Sstr2 has several biochemical functions, for example, PDZ domain binding,neuropeptide binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Sstr2 itself. We selected most functions Sstr2 had, and list some proteins which have the same functions with Sstr2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| somatostatin receptor activity | SSTR3,SSTR5,SSTR1,SSTR4 |
| PDZ domain binding | ACOX1,CFTR,LIN7B,Fzd4,SDC2,ATP2B2,CLCN3,GIPC1,LLGL2,CXXC4 |
| protein binding | PCGF2,MBP,PDE6D,UIMC1,NCAPD2,NCF1,MRAP2,GRIN2A,TSPAN6,CDC20B |
| neuropeptide binding | GALR1,MC4R,MRGPRX2,GPR149,OPRD1,ADCYAP1R1,SSTR4,OPRL1,SSTR1,OPRD1B |
Interacting Protein
Sstr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Sstr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Sstr2.
PIK3R1;SSTR3
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References
- Frati, A; Rouzier, R; et al. Expression of Somatostatin Type-2 and-4 Receptor and Correlation with Histological Type in Breast Cancer. ANTICANCER RESEARCH 34:3997-4003(2014).
- Agaimy, A; Buslei, R; et al. Comparative study of soft tissue perineurioma and meningioma using a five-marker immunohistochemical panel. HISTOPATHOLOGY 65:60-70(2014).
