SP7
-
Official Full Name
Sp7 transcription factor -
Overview
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation. -
Synonyms
SP7;Sp7 transcription factor;transcription factor Sp7;osterix;OSX;MGC126598;Sp 7;SP7_HUMAN;Zinc finger protein osterix;OTTHUMP00000242639;OTTHUMP00000242702;OI11
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SP7-12124Z | Recombinant Zebrafish SP7 | Mammalian Cell | Zebrafish | His |
|
|
| SP7-2723H | Recombinant Human SP7 Protein, His-tagged | E.coli | Human | His | Met19-Leu288 |
|
| SP7-5613H | Recombinant Human SP7 Protein (Ser370-Ile431), N-His tagged | E.coli | Human | His | Ser370-Ile431 |
|
Involved Pathway
SP7 involved in several pathways and played different roles in them. We selected most pathways SP7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SP7 has several biochemical functions, for example, metal ion binding,nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SP7 itself. We selected most functions SP7 had, and list some proteins which have the same functions with SP7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleic acid binding | SRSF7A,QKI2,RAG1,CL2,EAR2,N6AMT2,BLF,NIFK,GPATCH1,ZFP746 |
| metal ion binding | ZNF177,CAR5A,OVOL3,ZFP775,CALM4,DEAF1,TOPAZ1,HPDB,JUB,YBEY |
Interacting Protein
SP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SP7.
Resources
Research Area
Osteoclast MarkersOsteoblast and Osteoclast Markers
Osteogenesis Markers
Osteoblast Markers
Osteoprogenitor Markers
Related Services
Related Products
References
- Bozkurt, YA; Kus, S; et al. Histological and immunohistochemical studies of the structure of lymph nodes in Kilis goats. BIOTECHNIC & HISTOCHEMISTRY 89:440-445(2014).
- Rashid, H; Ma, CY; et al. Sp7 and Runx2 molecular complex synergistically regulate expression of target genes. CONNECTIVE TISSUE RESEARCH 55:83-87(2014).
