SOX14
-
Official Full Name
SRY (sex determining region Y)-box 14 -
Overview
The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate (specifically neuronal). SOX-14 is most closely related to SOX factors 1,2 and 3 and likely mirrors expression of these genes in the developing brain and spinal cord. -
Synonyms
SOX14;SRY (sex determining region Y)-box 14;transcription factor SOX-14;HMG box transcription factor SOX 14;SOX28;SRY box 14;SRY-box 14;HMG box transcription factor SOX-14;MGC119898;MGC119899
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Chicken
- Cynomolgus
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SOX14 involved in several pathways and played different roles in them. We selected most pathways SOX14 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SOX14 has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding,chromatin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX14 itself. We selected most functions SOX14 had, and list some proteins which have the same functions with SOX14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | FOXN2B,FOXR1,ARX,PAX6,SP3A,MITFA,SPI1,FOXD4L1,TP53,SOX21A |
| protein heterodimerization activity | DDIT3,BCL2L1,UGT1A4,CABYR,TERF1,MCL1,MYF5,IL12A,JAM2,HIST1H2AM |
| protein binding | UPK3A,CHAMP1,MTAP1B,COG5,FUNDC1,CPNE7,LDLRAP1,KIAA1530,ACTG1,RNF182 |
| chromatin binding | SMARCD1,UBTFL,SETD7,RING1,CEBPB,POLG,NCOA5,TOX2,MSL1A,SOX9A |
| sequence-specific DNA binding | SOX21B,FOXC1,RXRGA,LHX9,DLX4,PHOX2BB,DBX1A,MAF,FOXE1,NR1D4A |
Interacting Protein
SOX14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX14 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX14.
NAIF1;ZDHHC17
Resources
Related Services
Related Products
References
- Higuchi, M; Kanno, N; et al. GFP-expressing S100 beta-positive cells of the rat anterior pituitary differentiate into hormone-producing cells. CELL AND TISSUE RESEARCH 357:767-779(2014).
