SNX2
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Official Full Name
sorting nexin 2 -
Overview
Sorting nexin-2 is a protein that in humans is encoded by the SNX2 gene. -
Synonyms
SNX2;sorting nexin 2;sorting nexin-2;transformation-related gene 9 protein;TRG-9;MGC5204
Recombinant Proteins
- Mouse
- Chicken
- Zebrafish
- Rhesus macaque
- Cynomolgus
- Human
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
SNX2 involved in several pathways and played different roles in them. We selected most pathways SNX2 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | SMURF2,EHD1,DDL-2,SH3GL1A,ARF6B,VPS26A,TGFBR1,CAV1,SH3GL1B,PIP5K1BA |
Protein Function
SNX2 has several biochemical functions, for example, epidermal growth factor receptor binding,insulin receptor binding,leptin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX2 itself. We selected most functions SNX2 had, and list some proteins which have the same functions with SNX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | TFAP2B,TIMM9,HNF4A,ADD1,OLIG2,TGFB2,NOD1,SYT16,ZBTB1,CRYBA2 |
| leptin receptor binding | SNX1,SNX4 |
| insulin receptor binding | PTPN1,GRB10,IGF1,DOK4,INS,SNX1,IGF1R,DOK3,INSL3,PHIP |
| epidermal growth factor receptor binding | FAM83B,EPGN,VAV3,PLSCR1,GRB2,ERBB4,TNK2,LINGO1,ARF4,HBEGFA |
| protein heterodimerization activity | BHLHE40,HGF,HIST1H2BD,CREB3L3,SNX5,OSTB,ALG2,H3F3A,USF2,RBP4 |
| transferrin receptor binding | HFE,RGMA,SNX4,SNX1,TF,HFE2,Trf,CD81 |
| phosphatidylinositol binding | PIK3C2G,SNX17,SNX13,PLD2,TULP4,SNX1,NISCH,SNX25,ITPR2,SLC12A9 |
| protein binding | FOSL1,SYT16,DYNLT3,SLC25A4,NF2,CLIC2,PTGES2,CHD8,XPA,CRYBA1 |
Interacting Protein
SNX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX2.
FNBP1;VPS26A;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;ZNF202;LAMC1;CSNK2B;TSC22D1;VPS35;VPS29
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