SNAPIN

  • Product List
  • Overview
  • Review / Q&A
  • Official Full Name

    SNAP-associated protein
  • Overview

    The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble;N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis;of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of;the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1;complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules.;Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of;Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
  • Synonyms

    SNAPIN;SNAP-associated protein;SNAPAP;SNARE-associated protein Snapin;SNAP 25 binding protein;SNAP-25-binding protein;SNARE associated protein snapin;synaptosomal-associated protein 25-binding protein

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Rhesus macaque
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Avi
  • Fc
  • Flag
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
SNAPIN-2836H Recombinant Human SNAPIN, His-tagged E.coli Human His 0-136AA
SNAPAP-691H Recombinant Human SNAPAP Protein, His-tagged E.coli Human His Ala2~Lys136
SNAPIN-15672M Recombinant Mouse SNAPIN Protein Mammalian Cells Mouse His
SNAPIN-30508TH Recombinant Human SNAPIN, His-tagged E.coli Human His Full L.
SNAPIN-30509TH Recombinant Human SNAPIN, His-tagged E.coli Human His Full L.
SNAPIN-307H Recombinant Human SNAP-associated Protein E.coli Human His
SNAPIN-4181Z Recombinant Zebrafish SNAPIN Mammalian Cells Zebrafish His
SNAPIN-4365R Recombinant Rhesus monkey SNAPIN Protein, His-tagged Mammalian Cells Rhesus macaque His
SNAPIN-1635HCL Recombinant Human SNAPIN 293 Cell Lysate HEK293 Human Non
SNAPIN-2054H Recombinant Human SNAPIN Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
SNAPIN-2054H-B Recombinant Human SNAPIN Protein Pre-coupled Magnetic Beads HEK293 Human
SNAPIN-2091HFL Recombinant Full Length Human SNAPIN Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
SNAPIN-3210H Recombinant Human SNAPIN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
SNAPIN-4181R Recombinant Rhesus Macaque SNAPIN Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
SNAPIN-4181R-B Recombinant Rhesus Macaque SNAPIN Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Snapin-5995M Recombinant Mouse Snapin Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
SNAPIN-8523M Recombinant Mouse SNAPIN Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
SNAPIN-8523M-B Recombinant Mouse SNAPIN Protein Pre-coupled Magnetic Beads HEK293 Mouse

Involved Pathway

SNAPIN involved in several pathways and played different roles in them. We selected most pathways SNAPIN participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNAPIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Membrane Trafficking TRAPPC2L,CX30.3,TRAPPC2,MYO1C,TRAPPC1,SH3D19,GJB7,CTSZ,NAPB,ANKRD28
trans-Golgi Network Vesicle Budding GAK,NECAP1,BLOC1S4,FTH1A,SH3D19,FTH1B,CNO,CPD,SNX9,PICALM
Clathrin derived vesicle budding CLTB,APPB,TGOLN2,CLVS2,CLTA,SNX9A,NAPAB,DTNBP1,PPIAL4A,FTH1A
Golgi Associated Vesicle Biogenesis FTH1B,HIP1R,BLOC1S3,NECAP1,SH3D19,AP1S1,AP1B1,TFR1B,DTNBP1,TBC1D8B
Vesicle-mediated transport CPD,BLOC1S6,CNO,TERFA,CX27.5,PICALMA,GJA4,TRAPPC10,FTH1A,AP3S1

Protein Function

SNAPIN has several biochemical functions, for example, SNARE binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNAPIN itself. We selected most functions SNAPIN had, and list some proteins which have the same functions with SNAPIN. You can find most of the proteins on our site.

Function Related Protein
protein binding TEX13A,LOC149950,ASF1B,SIGIRR,ILF2,TMIGD2,PLEKHH2,EWSR1,MXD3,E4F1
SNARE binding GOSR2,SYT1,VAMP2,SEC22BB,TNFAIP2,VAMP7,VTI1A,SEC22BA,STX2A,STX1B

Interacting Protein

SNAPIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNAPIN here. Most of them are supplied by our site. Hope this information will be useful for your research of SNAPIN.

BLOC1S2;DTNBP1;LRRK2;Slc14a2

Resources

References

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