SMARCE1

  • Official Full Name

    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

  • Overview

    The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

  • Synonyms

    SMARCE1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1;BAF57;BRG1-associated factor 57;chromatin remodeli

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Rhesus macaque
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
SMARCE1-2807H Recombinant Human SMARCE1, GST-tagged E.coli Human GST C-term-323aa
SMARCE1-11446Z Recombinant Zebrafish SMARCE1 Mammalian Cells Zebrafish His
SMARCE1-1479C Recombinant Chicken SMARCE1 Mammalian Cells Chicken His
SMARCE1-4339R Recombinant Rhesus monkey SMARCE1 Protein, His-tagged Mammalian Cells Rhesus macaque His
SMARCE1-5615R Recombinant Rat SMARCE1 Protein Mammalian Cells Rat His
SMARCE1-1667HCL Recombinant Human SMARCE1 293 Cell Lysate HEK293 Human Non
SMARCE1-4155R Recombinant Rhesus Macaque SMARCE1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
SMARCE1-4155R-B Recombinant Rhesus Macaque SMARCE1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SMARCE1-5274R Recombinant Rat SMARCE1 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
SMARCE1-5274R-B Recombinant Rat SMARCE1 Protein Pre-coupled Magnetic Beads HEK293 Rat
Smarce1-5963M Recombinant Mouse Smarce1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    SMARCE1 involved in several pathways and played different roles in them. We selected most pathways SMARCE1 participated on our site, such as Androgen receptor signaling pathway,Chromatin modifying enzymes,Chromatin organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin organization EPC1,SMYD2A,KDM4B,KANSL3,SAP30L,CAPNS2,C20orf20,RBB4L,SMARCD1,KDM5BA
    TNF-alpha/NF-kB Signaling Pathway ZFAND5,TRAIP,TIFA,SMARCC2,KIAA1967,PPP1R13L,NKIRAS1,NR2C2,G3BP2,DAP
    Regulation of Androgen receptor activity SENP1,NR2C1,GATA2,NR2C2,HOXB13,NR0B1,APPBP2,SMARCA2,SPDEF,KAT7
    Androgen receptor signaling pathway RANBP9,NR0B2A,PATZ1,POU2F1B,GNB2L1,KAT7,RNF6,SMAD3B,NCOA2,ETV5A
    Chromatin modifying enzymes KDM2AA,ACTL6A,KDM6B,C20orf20,ATXN7L3,SAP130,SMARCC1,TADA2B,KDM4B,DNMT3A
    RMTs methylate histone arginines ARID1A,PRMT7,SMARCB1B,SMARCC1,PBRM1L,SMARCB1,SMARCB1A,WDR77,PBRM1,SMARCC2

    Protein Function

    SMARCE1 has several biochemical functions, for example, N-acetyltransferase activity,RNA binding,contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCE1 itself. We selected most functions SMARCE1 had, and list some proteins which have the same functions with SMARCE1. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to nucleosomal DNA binding HDAC2,RBBP4,HDAC1,ACTB,ACTL6A,SMARCA4,CHD4,SMARCC2,SMARCB1,MBD3
    protein N-terminus binding PARP1,RBPJ,GLRX,TAF11,EIF5A,ERCC6,KCNIP1,PHB2,PEX5,SCFD1
    chromatin binding HDAC5,BRD3,HMGB4,NSD1,SNAI2,SOX15,APTX,MEIOB,ATXN7,NFKB1
    ligand-dependent nuclear receptor binding SRA1,ISL1,C1D,NCOA2,JUND,TRIM24,NCOR2,ARID1A,PPARGC1A,MED1
    contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding MBD3,ACTL6A,SMARCC2,MTA2,SMARCC1,ACTB,SMARCA4,SMARCB1,HDAC2,HDAC1
    N-acetyltransferase activity MBOAT1,CML2,NAA40,AANAT1,SAT1B,Acnat1,NAT14,SAT2A,MBOAT4,CML5
    protein binding NAP1L2,MIS18BP1,ANKRD17,SRPK3,MTPAP,KIAA1279,AIM2,HRG,IL17RA,DAG1
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding SMARCC2,SMARCA4,HDAC1,SMARCB1,MTA2,SMARCC1,ACTB,RBBP4,ACTL6A,CHD4
    RNA binding CSTF3,PSMA1,ILF3B,HDLBPA,CRNKL1,YY1,RPL11,METTL3,WDHD1,TIMM50

    Interacting Protein

    SMARCE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCE1.

    CEP63;KIFC3;BRMS1;ARID2;MEOX2;285622

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