SMARCE1

  • Official Full Name

    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

  • Overview

    The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

  • Synonyms

    SMARCE1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1;BAF57;BRG1-associated factor 57;chromatin remodeli

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Rhesus macaque
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • GST
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
SMARCE1-2807H Recombinant Human SMARCE1, GST-tagged E.coli Human GST C-term-323aa
SMARCE1-11446Z Recombinant Zebrafish SMARCE1 Mammalian Cell Zebrafish His
SMARCE1-1479C Recombinant Chicken SMARCE1 Mammalian Cell Chicken His
SMARCE1-4339R Recombinant Rhesus monkey SMARCE1 Protein, His-tagged Mammalian Cell Rhesus macaque His
SMARCE1-5615R Recombinant Rat SMARCE1 Protein Mammalian Cell Rat His
SMARCE1-1667HCL Recombinant Human SMARCE1 293 Cell Lysate HEK293 Human Non
SMARCE1-4155R Recombinant Rhesus Macaque SMARCE1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
SMARCE1-4155R-B Recombinant Rhesus Macaque SMARCE1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SMARCE1-5274R Recombinant Rat SMARCE1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
SMARCE1-5274R-B Recombinant Rat SMARCE1 Protein Pre-coupled Magnetic Beads HEK293 Rat
Smarce1-5963M Recombinant Mouse Smarce1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    SMARCE1 involved in several pathways and played different roles in them. We selected most pathways SMARCE1 participated on our site, such as Androgen receptor signaling pathway,Chromatin modifying enzymes,Chromatin organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin organization ING5A,ATXN7,KDM7AB,ACTL6B,ING5,ARID5B,KIAA1267,PADI4,SUDS3,EED
    TNF-alpha/NF-kB Signaling Pathway TRPC4AP,TANK,CRADD,PAPOLA,LRPPRC,AKAP8,PFDN2,DPF2,DCAF7,DDX3X
    Regulation of Androgen receptor activity SPDEF,NR0B1,SENP1,NR2C2,SMARCA2,KAT7,GATA2,NR2C1,APPBP2,SRY
    Androgen receptor signaling pathway JUN,HMGB2A,TGFB1I1,STUB1,CMTM2A,DAXX,PIAS3,EGFR,SVILA,KAT7
    RMTs methylate histone arginines WDR77,PBRM1L,ARID1A,SMARCD3B,SMARCB1B,SMARCB1A,SMARCD1,PBRM1,SMARCB1,COPRS
    Chromatin modifying enzymes ENY2,RBBP5,SMARCB1B,ING5B,PRDM16,KAT5,BRD1,SMARCB1A,MSL1A,ACTL6B

    Protein Function

    SMARCE1 has several biochemical functions, for example, N-acetyltransferase activity,RNA binding,contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCE1 itself. We selected most functions SMARCE1 had, and list some proteins which have the same functions with SMARCE1. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding SRSF3,CPSF2,SNRPF,RBMY1F,JAKMIP1,TRIM32,HNRNPC,KHDC1A,FARSB,HNRNPA1
    N-acetyltransferase activity NAT9,DGAT2L6,LPCAT3,NAA10,MBOAT1,HHAT,CML2,SAT2A,NAT10,NAA40
    protein binding HNRNPU,MUC7,MAGEA9,RPAP1,FAM13C,ZDHHC13,DNAJB4,HSP90AB1,ZNF224,IL1RL1
    transcription coactivator activity TAF12,RFXAP,NCOA4,TBPL1,JUNB,NCOA2,RB1,CDK7,CARM1,MED1
    ligand-dependent nuclear receptor binding TRIP4,MED1,UBA3,JUND,NR1H4,SLC30A9,TRIM24,NCOR2,ARID1A,NCOA1
    protein N-terminus binding SNCA,PPP1CC,EXOC4,GTF2H2,ERCC3,SMARCA4,MEN1,EIF3E,MNAT1,MAP2K1
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding MBD3,CHD4,HDAC2,SMARCC2,SMARCB1,GATAD2B,RBBP4,SMARCC1,ACTB,ACTL6A
    contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding SMARCC2,SMARCC1,HDAC2,SMARCB1,ACTL6A,GATAD2B,HDAC1,MTA2,CHD4,MBD3
    chromatin binding PAX3,MTA3,POU2F1,EZH2,STAG2,BRD3,SIRT6,MEIS3,SUZ12,JUN

    Interacting Protein

    SMARCE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCE1.

    CEP63;KIFC3;BRMS1;ARID2;MEOX2;285622

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All SMARCE1 Products

    Required fields are marked with *

    My Review for All SMARCE1 Products

    Required fields are marked with *