SMARCC1
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Official Full Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -
Overview
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008] -
Synonyms
SMARCC1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1;Rsc8;SRG3;SWI3;BAF155;CRACC1;SWI/SNF complex subunit SMARCC1;BRG1-associated factor 155;SWI/SNF complex 155 kDa subunit;chromatin remodeling complex BAF155 subunit;mammalian chromatin remodeling complex BRG1-associated factor 155;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- Insect Cell
- His
- His&SUMO
- Myc&DDK
- His&Fc&Avi
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
SMARCC1-15602M | Recombinant Mouse SMARCC1 Protein | Mammalian Cell | Mouse | His | ||
SMARCC1-1068H | Recombinant Human SMARCC1 Protein (449-669 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 449-669 aa | |
SMARCC1-1911H | Recombinant Human SMARCC1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK | ||
SMARCC1-2348H | Recombinant Human SMARCC1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK | ||
SMARCC1-2741H | Recombinant Human SMARCC1 Protein (449-669 aa), His-tagged | Insect Cell | Human | His | 449-669 aa | |
SMARCC1-4641H | Recombinant Human SMARCC1 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 451-671aa | |
Smarcc1-5961M | Recombinant Mouse Smarcc1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK | ||
SMARCC1-8465M | Recombinant Mouse SMARCC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi | ||
SMARCC1-8465M-B | Recombinant Mouse SMARCC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
Involved Pathway
SMARCC1 involved in several pathways and played different roles in them. We selected most pathways SMARCC1 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,PluriNetWork, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Chromatin modifying enzymes | SAP130,PADI2,ACTL6B,CAPNS2,BRMS1,SMYD3,TADA1,DNMT3A,RBB4L,ATF7IP |
TNF-alpha NF-kB Signaling Pathway | ZFAND5A,TRPC4APA,CASP8AP2,NLRP4E,MTIF2,CAPN3A,IKBKAP,SMARCB1A,TRAF4A,SMARCA4A |
PluriNetWork | ZMYM2,IPO7,ZFP143,XPO4,ZFP57,ZSCAN10,SALL3,KLF5,RCOR2 |
Chromatin organization | DMAP1,MBD3A,PADI6,EPC1,PHF15,SMYD2,SMARCD3,CHD4,KDM4D,YEATS4 |
RMTs methylate histone arginines | SMARCD3B,SMARCE1,SMARCA4,PRMT7,SMARCC2,SMARCC1B,SMARCB1,ACTL6B,SMARCA2,SMARCD3 |
Protein Function
SMARCC1 has several biochemical functions, for example, DNA binding,contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding,contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCC1 itself. We selected most functions SMARCC1 had, and list some proteins which have the same functions with SMARCC1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
chromatin binding | BAP1,CDK9,SIX1,CDCA5,HIST2H3C1,HDAC7,BRD4,TCF7L1B,PELP1,HDGFRP2 |
contributes_to nucleosomal DNA binding | ACTL6A,SMARCA4,MBD3,SMARCB1,ACTB,HDAC2,GATAD2B,CHD4,HDAC1,SMARCC2 |
DNA binding | ZNF791,PREB,ZNF222,FOXJ1A,HIST1H2AD,ERG,ZNF606,ZNF707,PCBP2,ESR2A |
contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding | ACTL6A,RBBP4,SMARCE1,SMARCB1,CHD4,ACTB,SMARCC2,MBD3,HDAC1,GATAD2B |
contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding | HDAC1,RBBP4,MTA2,GATAD2B,ACTL6A,SMARCA4,ACTB,SMARCE1,CHD4,SMARCB1 |
protein N-terminus binding | KCNB1,PEX5,GTF2H3,SMARCE1,YWHAQ,ERCC6,CSNK2A1,PEX14,ERCC5,MYO7A |
protein binding | C4orf46,GLI3,SLX4,TRIM29,MRPL13,DPM3,ARMC1,FYTTD1,SOX7,FXYD6 |
Interacting Protein
SMARCC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCC1.
Smarca4;Smarcb1;Smarcd1;Smarce1;Pou5f1;Sox2
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