Slc6a2
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Official Full Name
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 -
Synonyms
SLC6A2;solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2;ENSMUSG00000055368;NET;NE-T;Slc6a5;8 C5;8 45.0 cM;sodium-dependent noradrenaline transporter;sodium-dependent noradrenaline transporter;NE transporter;norepinephrine transporter;solute carrier family 6 member 2;EC 2.3.1.5
Recombinant Proteins
- Mouse
- Rabbit
- Rhesus macaque
- Chicken
- Human
- Mammalian Cells
- E.Coli/Yeast
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC6A2-15500M | Recombinant Mouse SLC6A2 Protein | Mammalian Cells | Mouse | His |
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| SLC6A2-3652R | Recombinant Rabbit SLC6A2, His-tagged | E.Coli/Yeast | Rabbit | His | 290 |
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| SLC6A2-4304R | Recombinant Rhesus monkey SLC6A2 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| SLC6A2-6281C | Recombinant Chicken SLC6A2 | Mammalian Cells | Chicken | His |
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| SLC6A2-1919H | Recombinant Human SLC6A2 protein, His-tagged | HEK293 | Human | His | Phe 167 - Pro 233 |
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| SLC6A2-4120R | Recombinant Rhesus Macaque SLC6A2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SLC6A2-4120R-B | Recombinant Rhesus Macaque SLC6A2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| SLC6A2-8409M | Recombinant Mouse SLC6A2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SLC6A2-8409M-B | Recombinant Mouse SLC6A2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Slc6a2 involved in several pathways and played different roles in them. We selected most pathways Slc6a2 participated on our site, such as Na+/Cl- dependent neurotransmitter transporters,SLC-mediated transmembrane transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with Slc6a2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | BEST4,BEST3,SLC38A5B,SLC29A4,CLCN1A,AQP6,SLCO4C1,ABCA8,NIPA1,ABCF1 |
| XPodNet - protein-protein interactions in the podocyte expanded by STRING | MTAP1A,CMIP,FAM65A,ZFP423,CDC42EP5,FRAS1,SNTB1,MICALL2,ARHGAP32,PKD1 |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | RHCGB,RHCGL1,SLC2A13,SLC6A7,SLC22A7B.1,RHCG2A,SLC6A20A,SLC39A8,SLC16A7,SLC6A19A |
| Na+/Cl- dependent neurotransmitter transporters | SLC6A12,SLC6A1B,SLC6A15,SLC6A19A,SLC6A6,SLC6A20,SLC6A9,SLC6A1A,SLC6A6A,SLC6A18 |
| SLC-mediated transmembrane transport | SLC15A1B,SLCO4A1,PDZD11,SLC20A2,SLC6A1A,SLC7A3A,SLC6A9,SLC29A4,SLC7A6,SLC39A3 |
Protein Function
Slc6a2 has several biochemical functions, for example, alpha-tubulin binding,beta-tubulin binding,monoamine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Slc6a2 itself. We selected most functions Slc6a2 had, and list some proteins which have the same functions with Slc6a2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| symporter activity | SLC24A1,SLC6A18,SLC6A19B,SLC38A3,SLC17A8,SLC17A4,SLC13A1,SLC5A8L,SLC16A7,SLC1A2A |
| alpha-tubulin binding | PACRG,PPARGC1A,DDL-2,FAM110C,NDEL1,WASH,ARL8B,ARL8A,PROL1,HDAC6 |
| monoamine transmembrane transporter activity | SLC18A2,SLC6A3,SLC29A4,SLC22A1,SLC6A4,SLC18A1 |
| neurotransmitter:sodium symporter activity | SLC6A16B,SLC6A1B,SLC6A7,SLC6A15,SLC6A8,SLC6A6,SLC6A20B,SLC6A11,SLC6A19B,SLC6A18 |
| norepinephrine transmembrane transporter activity | SLC22A1 |
| beta-tubulin binding | RANBP10,ARL8A,RGS2,CCT5,HTT,MAP1S,AKAP1,SNCA,LRPPRC,IFT74 |
Interacting Protein
Slc6a2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Slc6a2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Slc6a2.
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References
- Shang, CY; Chiang, HL; et al. A haplotype of the norepinephrine transporter gene (SLC6A2) is associated with visual memory in attention-deficit/hyperactivity disorder. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 58:89-96(2015).
- Proft, F; Kopf, J; et al. SLC6A2 and SLC6A4 variants interact with venlafaxine serum concentrations to infl uence therapy outcome (vol 47, pg 245, 2014). PHARMACOPSYCHIATRY 48:81-81(2015).
