SLC43A2
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Official Full Name
solute carrier family 43, member 2 -
Overview
System L amino acid transporters, such as SLC43A2, mediate sodium-independent transport of bulky neutral amino acids;across cell membranes (Bodoy et al., 2005 (PubMed 15659399)). -
Synonyms
SLC43A2;solute carrier family 43, member 2;large neutral amino acids transporter small subunit 4;MGC34680;amino acid transporter;L-type amino acid transporter 4;LAT4;FLJ23848
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Mammalian Cell
- HEK293
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
SLC43A2 involved in several pathways and played different roles in them. We selected most pathways SLC43A2 participated on our site, such as Amino acid transport across the plasma membrane,SLC-mediated transmembrane transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC43A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SLC-mediated transmembrane transport | SLC4A2B,SLC2A6,SLC24A5,SLC7A8A,SLC6A20A,SLC35B3,PDZD11,RHCGA,SLC35A3B,SLC15A1B |
| Transmembrane transport of small molecules | CLIC2,SLC29A2,FXYD7,Ano3,TRPC4AP,SRI,WNK2,SLC30A3,SLC6A20,SLC1A2A |
| Amino acid transport across the plasma membrane | SLC43A1B,SLC6A18,SLC3A2A,SLC43A1A,SLC43A2A,SLC7A11,SLC3A2B,SLC7A8A,SLC6A19A,SLC6A19B |
| Transport of inorganic cations/anions and amino acids/oligopeptides | SLC6A18,SLC1A7A,SLC7A8A,SLC20A1B,SLC26A3.1,SLC43A1A,SLC17A7A,SLC4A2B,SLC24A5,SLC12A3 |
Protein Function
SLC43A2 has several biochemical functions, for example, L-amino acid transmembrane transporter activity,neutral amino acid transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC43A2 itself. We selected most functions SLC43A2 had, and list some proteins which have the same functions with SLC43A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| L-amino acid transmembrane transporter activity | SLC43A2A,SLC43A2B,SLC43A1B,SLC7A5,SLC7A13,SLC43A1A,Nat3,SLC38A7,SLC7A8,SLC7A14 |
| neutral amino acid transmembrane transporter activity | SLC43A2A,SLC43A1B,SLC15A1B,SLC3A2,SLC43A1A,SLC1A5,SLC6A19A,SLC6A19B,SLC43A2B,SLC38A5 |
Interacting Protein
SLC43A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC43A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC43A2.
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References
- Chen, C; Zhang, CL; et al. Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia. BIPOLAR DISORDERS 16:790-799(2014).
- Motaghed, M; Al-Hassan, FM; et al. Thymoquinone regulates gene expression levels in the estrogen metabolic and interferon pathways in MCF7 breast cancer cells. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 33:8-16(2014).
