SLC38A4
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Official Full Name
solute carrier family 38, member 4 -
Overview
SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic;amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH;dependent (Hatanaka et al., 2001 (PubMed 11342143)). -
Synonyms
SLC38A4;solute carrier family 38, member 4;sodium-coupled neutral amino acid transporter 4;ATA3;NAT3;PAAT;amino acid transporter A3;N amino acid transporter 3;amino acid transporter system A3;system A amino acid transporter 3;system N amino acid
Recombinant Proteins
- Zebrafish
- Mouse
- Chicken
- Rat
- Mammalian Cell
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC38A4-1477Z | Recombinant Zebrafish SLC38A4 | Mammalian Cell | Zebrafish | His |
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| SLC38A4-15424M | Recombinant Mouse SLC38A4 Protein | Mammalian Cell | Mouse | His |
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| SLC38A4-4383C | Recombinant Chicken SLC38A4 | Mammalian Cell | Chicken | His |
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| SLC38A4-5526R | Recombinant Rat SLC38A4 Protein | Mammalian Cell | Rat | His |
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| SLC38A4-5185R | Recombinant Rat SLC38A4 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SLC38A4-5185R-B | Recombinant Rat SLC38A4 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| SLC38A4-8356M | Recombinant Mouse SLC38A4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SLC38A4-8356M-B | Recombinant Mouse SLC38A4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SLC38A4 involved in several pathways and played different roles in them. We selected most pathways SLC38A4 participated on our site, such as Amino acid transport across the plasma membrane,SLC-mediated transmembrane transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC38A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Amino acid transport across the plasma membrane | SLC43A2,SLC7A3A,SLC43A2B,SLC7A6,SLC38A5B,SLC3A2A,SLC6A15,SLC6A18,SLC7A3,SLC6A20A |
| SLC-mediated transmembrane transport | SLC2A6,CTNS,SLC35D1A,SLC22A7B.1,SLC6A6,SLC39A10,SLC30A6,SLC7A6,SLC6A20B,SLC22A7 |
| Transport of inorganic cations/anions and amino acids/oligopeptides | SLC15A2,SLC4A4A,SLC7A3A,CTNS,SLC6A6,SLC7A6,SLC43A2,SLC6A20,SLC43A2B,SLC1A7B |
| Transmembrane transport of small molecules | SLC26A3,SLC28A2,TRPM1B,ANO10A,SLC9A7,SLC22A17,HTR3C,ANKHA,SLC17A1,SLC6A20A |
Protein Function
SLC38A4 has several biochemical functions, for example, amino acid transmembrane transporter activity,symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC38A4 itself. We selected most functions SLC38A4 had, and list some proteins which have the same functions with SLC38A4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| symporter activity | SLC6A20A,SLC4A11,SLC24A5,SLC13A1,SLC6A6B,SLC10A5,SLC1A2B,SLC16A12,SLC46A2,SLC1A8B |
| amino acid transmembrane transporter activity | SLC7A8,PEX3,SLC7A6,SLC7A14,SLC38A2,SLC3A1,SLC7A5,SLC38A6,SLC38A9,SLC38A5 |
Interacting Protein
SLC38A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC38A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC38A4.
Ywhae
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References
- Hagglund, MGA; Sreedharan, S; et al. Identification of SLC38A7 (SNAT7) Protein as a Glutamine Transporter Expressed in Neurons. JOURNAL OF BIOLOGICAL CHEMISTRY 286:20500-20511(2011).
