SLC25A6
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Official Full Name
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -
Overview
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. -
Synonyms
SLC25A6;solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 6;ANT3;ADP/ATP translocase 3;ANT3Y;MGC17525;Adenine nucleotide translocator 3;ADP ATP carrier protein 3;ADP ATP carrier protein isoform T2;ADP ATP carrier protein liver;ADP/ATP translocator of liver;ANT 3;Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6;Solute carrier family 25 member 6;ANT 2;OTTHUMP00000022826;ADP,ATP carrier protein 3;ADP,ATP carrier protein, liver;ADP,ATP carrier protein, isoform T2;AAC3
Recombinant Proteins
- Human
- Bovine
- Chicken
- Zebrafish
- Cynomolgus
- Sus scrofa (Pig)
- E.coli
- E.Coli/Yeast
- Mammalian Cells
- HEK293
- GST
- His
- Non
- KSI
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SLC25A6-2731H | Recombinant Human SLC25A6, GST-tagged | E.coli | Human | GST | 1-298aa | |
| SLC25A6-3223B | Recombinant Bovine SLC25A6, His-tagged | E.Coli/Yeast | Bovine | His | 298 |
|
| SLC25A6-5804C | Recombinant Chicken SLC25A6 | Mammalian Cells | Chicken | His |
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| SLC25A6-7005Z | Recombinant Zebrafish SLC25A6 | Mammalian Cells | Zebrafish | His |
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| SLC25A6-928C | Recombinant Cynomolgus SLC25A6 Protein, His-tagged | Mammalian Cells | Cynomolgus | His |
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| SLC25A6-1756HCL | Recombinant Human SLC25A6 293 Cell Lysate | HEK293 | Human | Non |
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| RFL10343BF | Recombinant Full Length Bovine Adp/Atp Translocase 3(Slc25A6) Protein, His-Tagged | E.coli | Bovine | His | Full L. Full Length of Mature Protein (2-298) |
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| RFL29836HF | Recombinant Full Length Human Adp/Atp Translocase 3(Slc25A6) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length of Mature Protein (2-298) |
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| RFL6096SF | Recombinant Full Length Pig Adp/Atp Translocase 3(Slc25A6) Protein, His-Tagged | E.coli | Sus scrofa (Pig) | His | Full L. Full Length of Mature Protein (2-298) |
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| SLC25A6-2732H | Recombinant Human SLC25A6 protein, His-KSI-tagged | E.coli | Human | His&KSI | 232-272aa |
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| SLC25A6-671C | Recombinant Cynomolgus Monkey SLC25A6 Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | Avi&Fc&His |
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| SLC25A6-671C-B | Recombinant Cynomolgus Monkey SLC25A6 Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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Involved Pathway
SLC25A6 involved in several pathways and played different roles in them. We selected most pathways SLC25A6 participated on our site, such as Calcium signaling pathway,cGMP-PKG signaling pathway,Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| cGMP-PKG signaling pathway | TRPC6,PPP3CB,CALML5,ATP2A3,ATP2B1,PIK3CA,PIK3CD,SLC8A1,PIK3R1,ROCK1 |
| Influenza A | PLG,FURIN,CASP1,PRKCA,STAT1,NFKBIA,IFNA21,IFNA4,IL8L1,AGFG1 |
| Parkinsons disease | DRD1A,NDUFA4L2,COX7A1,NDUFA8,ATP5A1,NDUFAB1,SLC25A4,VDAC2,ATP5F1,UQCRFS1 |
| Calcium signaling pathway | SLC25A31,GNAS,AVPR1A,CHRM5,ORAI1B,ADCY2B,PPP3CA,ADRB2A,PLCD3A,CACNA1SB |
| HTLV-I infection | WNT6,HLA-B,WNT3A,DVL3,TGFB1,PRKACA,PIK3R3,SMAD4,ITGAL,POLE4 |
| Huntingtons disease | POLR2L,UQCRC2,VDAC2,CREB3L3,DNAH14,TRP53,ATP5G1,NDUFB11,DNAH6,NDUFB7 |
Protein Function
SLC25A6 has several biochemical functions, for example, ATP:ADP antiporter activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A6 itself. We selected most functions SLC25A6 had, and list some proteins which have the same functions with SLC25A6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HSPA1L,TOMM22,MTMR14,NFE2L1,GSTK1,OGFR,RNF149,CLDN18,MPRIP,TAF1 |
Interacting Protein
SLC25A6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A6.
MTUS2;TRIM23;AP2B1;TRAF1;KRT31;TRIP6;LRRK2
Resources
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References
- Ji, H; Wang, JF; et al. Expression of Eleven Egg Performance-associated Genes in the Ovary of Zi Geese Anser anser domestica. JOURNAL OF POULTRY SCIENCE 50:91-98(2013).
- Clemencon, B; Babot, M; et al. The mitochondrial ADP/ATP carrier (SLC25 family): Pathological implications of its dysfunction. MOLECULAR ASPECTS OF MEDICINE 34:485-493(2013).
