SLC25A6

  • Official Full Name

    solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
  • Overview

    This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.
  • Synonyms

    SLC25A6;solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 6;ANT3;ADP/ATP translocase 3;ANT3Y;MGC17525;Adenine nucleotide translocator 3;ADP ATP carrier protein 3;ADP ATP carrier protein isoform T2;ADP ATP carrier protein liver;ADP/ATP translocator of liver;ANT 3;Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6;Solute carrier family 25 member 6;ANT 2;OTTHUMP00000022826;ADP,ATP carrier protein 3;ADP,ATP carrier protein, liver;ADP,ATP carrier protein, isoform T2;AAC3

Recombinant Proteins

  • Human
  • Bovine
  • Chicken
  • Zebrafish
  • Cynomolgus
  • Sus scrofa (Pig)
  • E.coli
  • E.Coli or Yeast
  • Mammalian Cell
  • HEK293
  • E.coli expression system
  • GST
  • His
  • Non
  • His&KSI
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SLC25A6-2731H Recombinant Human SLC25A6, GST-tagged E.coli Human GST 1-298aa
SLC25A6-3223B Recombinant Bovine SLC25A6, His-tagged E.Coli or Yeast Bovine His 298
SLC25A6-5804C Recombinant Chicken SLC25A6 Mammalian Cell Chicken His
SLC25A6-7005Z Recombinant Zebrafish SLC25A6 Mammalian Cell Zebrafish His
SLC25A6-928C Recombinant Cynomolgus SLC25A6 Protein, His-tagged Mammalian Cell Cynomolgus His
SLC25A6-1756HCL Recombinant Human SLC25A6 293 Cell Lysate HEK293 Human Non
RFL10343BF Recombinant Full Length Bovine Adp/Atp Translocase 3(Slc25A6) Protein, His-Tagged E.coli expression system Bovine His Full L. Full Length of Mature Protein (2-298)
RFL29836HF Recombinant Full Length Human Adp/Atp Translocase 3(Slc25A6) Protein, His-Tagged E.coli expression system Human His Full L. Full Length of Mature Protein (2-298)
RFL6096SF Recombinant Full Length Pig Adp/Atp Translocase 3(Slc25A6) Protein, His-Tagged E.coli expression system Sus scrofa (Pig) His Full L. Full Length of Mature Protein (2-298)
SLC25A6-2732H Recombinant Human SLC25A6 protein, His-KSI-tagged E.coli Human His&KSI 232-272aa
SLC25A6-671C Recombinant Cynomolgus Monkey SLC25A6 Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus His&Fc&Avi
SLC25A6-671C-B Recombinant Cynomolgus Monkey SLC25A6 Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus

    Involved Pathway

    SLC25A6 involved in several pathways and played different roles in them. We selected most pathways SLC25A6 participated on our site, such as Calcium signaling pathway,cGMP-PKG signaling pathway,Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway ATP1A2,TRPC6,GNAQ,PLCB3,CREB3L2,RHOA,BDKRB2,PPP3R1,CALM4,PIK3CD
    Calcium signaling pathway HTR2B,GRIN1B,CACNA1SB,CACNA1SA,GNAL,ITPKA,PTK2BB,CAMK2A,PLCZ1,HTR4
    Parkinsons disease NDUFV2,UBE1Y1,TH,NDUFB10,ATP5J,NDUFA3,PRKACA,ATP5B,APAF1,Casp3
    Huntingtons disease UQCRH,CREB3L3,SLC25A31,DNALC4,DNAL4,POLR2C,DCTN2,TBPL2,DNAH14,NDUFA11
    Influenza A TMPRSS2,PRSS2,IFNA4,PRSS3,MAPK8,IFNA1,IL33,MAP2K7,NFKBIB,NXF1
    HTLV-I infection VDAC1,EP300,HLA-DRA,ITGAL,CREM,PPP3R1,PIK3CA,LTA,MSX1,RANBP1

    Protein Function

    SLC25A6 has several biochemical functions, for example, ATP:ADP antiporter activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A6 itself. We selected most functions SLC25A6 had, and list some proteins which have the same functions with SLC25A6. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TLE1,ANXA9,EAF1,CREB3,INIP,PODXL,INO80B,SMG5,CDK7,SYTL4

    Interacting Protein

    SLC25A6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A6.

    MTUS2;TRIM23;AP2B1;TRAF1;KRT31;TRIP6;LRRK2

    Resources

    References

    • Ji, H; Wang, JF; et al. Expression of Eleven Egg Performance-associated Genes in the Ovary of Zi Geese Anser anser domestica. JOURNAL OF POULTRY SCIENCE 50:91-98(2013).
    • Clemencon, B; Babot, M; et al. The mitochondrial ADP/ATP carrier (SLC25 family): Pathological implications of its dysfunction. MOLECULAR ASPECTS OF MEDICINE 34:485-493(2013).

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