SLC1A5
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Official Full Name
solute carrier family 1 (neutral amino acid transporter), member 5 -
Overview
The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011] -
Synonyms
SLC1A5;solute carrier family 1 (neutral amino acid transporter), member 5;R16;AAAT;ATBO;M7V1;RDRC;ASCT2;M7VS1;neutral amino acid transporter B(0);ATB(0);RD114 virus receptor;baboon M7 virus receptor;neutral amino acid transporter B;solute carrier family 1 member 5;RD114/simian type D retrovirus receptor;sodium-dependent neutral amino acid transporter type 2
Recombinant Proteins
- Human
- Zebrafish
- Cynomolgus
- E.coli
- HEK293
- Mammalian Cells
- Insect Cells
- GST
- Non
- His&GST
- His
- His&TrxA
- His&Flag&MBP
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RDRC-2241H | Recombinant Human RDRC protein, GST-tagged | E.coli | Human | GST | C-106aa | |
| SLC1A5-0913H |
Active Recombinant Human SLC1A5 Full Length Transmembrane protein(Nanodisc)
|
HEK293 | Human | Non | Full L. |
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| SLC1A5-1195H | Recombinant Human SLC1A5 protein, His & GST-tagged | E.coli | Human | His&GST | Leu327~Met541 |
|
| SLC1A5-7769Z | Recombinant Zebrafish SLC1A5 | Mammalian Cells | Zebrafish | His |
|
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| SLC1A5-922C | Recombinant Cynomolgus SLC1A5 Protein, His-tagged | Mammalian Cells | Cynomolgus | His |
|
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| SLC1A5-1028H | Recombinant Human SLC1A5 protein, His & TrxA-tagged | E.coli | Human | His&TrxA | Gln 154 - Gln 224 |
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| SLC1A5-1210H | Recombinant Human SLC1A5 Protein (A2-F921), 8×His-MBP, Flag tagged | Insect Cells | Human | His&Flag&MBP | A2-F921 |
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| SLC1A5-665C | Recombinant Cynomolgus Monkey SLC1A5 Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | His&Fc&Avi |
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| SLC1A5-665C-B | Recombinant Cynomolgus Monkey SLC1A5 Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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Involved Pathway
SLC1A5 involved in several pathways and played different roles in them. We selected most pathways SLC1A5 participated on our site, such as Protein digestion and absorption,Central carbon metabolism in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC1A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein digestion and absorption | SLC38A2,COL15A1,COL6A4,CTRL,SLC1A1,PRSS3,ATP1A3,COL6A6,COL18A1,MME |
| Central carbon metabolism in cancer | IDH1,SLC2A1,PDGFRA,SLC7A5,PIK3CA,AKT1,NTRK1,HIF1A,PKM,G6PDX |
Protein Function
SLC1A5 has several biochemical functions, for example, L-glutamine transmembrane transporter activity,neutral amino acid transmembrane transporter activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC1A5 itself. We selected most functions SLC1A5 had, and list some proteins which have the same functions with SLC1A5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sodium:dicarboxylate symporter activity | SLC1A7,SLC1A1,SLC1A2A,SLC1A7B,SLC1A3B,SLC1A6,SLC1A2B,SLC13A3,SLC1A2,SLC1A3 |
| receptor activity | ITGB3B,PVRL2L,PAQR9,CADM4,RPA1,ADIPOR1B,CALCR,NLGN1,GRIK5,TNFRSF11B |
| virus receptor activity | AXL,ITGB3,PVRL1,CXCR4,NCAM1,ITGA5,CD209A,SERPINB3,HSPA1B,HAVCR1 |
| neutral amino acid transmembrane transporter activity | SLC7A10,SLC43A1B,SLC38A5,SLC6A19B,SLC7A8,SLC3A2,SLC6A19A,SLC43A1A,SLC43A2,SLC43A2A |
| protein binding | TAP1,LMX1B,RPLP1,C16orf48,MTPAP,PPID,MAGED1,IFT27,IGSF1,MEX3C |
| L-glutamine transmembrane transporter activity | SLC38A1,SLC38A7,SLC1A4,SLC38A3 |
Interacting Protein
SLC1A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC1A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC1A5.
RNF5;bnps-skatole;ganglioside_gm1;4504987;MPDU1;USP19;TNFRSF1A;TNFRSF1B;HLA-B;MAP3K1;USP50;NEK6;GSTK1;TBC1D17;15-deoxy-delta(12,14
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References
- Indo, Y; Takeshita, S; et al. Metabolic Regulation of Osteoclast Differentiation and Function. JOURNAL OF BONE AND MINERAL RESEARCH 28:2392-2399(2013).
- Metzler, R; Meleshkevitch, EA; et al. An SLC6 transporter of the novel B-0,B-- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans. JOURNAL OF EXPERIMENTAL BIOLOGY 216:2843-2857(2013).
