SGK2

  • Official Full Name

    serum/glucocorticoid regulated kinase 2

  • Overview

    Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort

  • Synonyms

    SGK2;serum/glucocorticoid regulated kinase 2;serine/threonine-protein kinase Sgk2;H-SGK2;dJ138B7.2

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Sf9 Cells
  • Mammalian Cells
  • HEK293
  • Insect Cells
  • Sf21 Cells
  • GST
  • His
  • T7
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway,Insulin Signaling,Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transmembrane transport of small molecules SLC9A7,SLC13A5A,SLC43A2B,SLC7A8A,SLC6A19B,SRI,SLC38A3,SLC7A3,SLC22A16,SLC38A5B
    Insulin Signaling MAP3K9,GRB10,STXBP3,MYO1C,SNAP25A,REG1A,KIF5B,GRB14,MINK1,STXBP4
    PI3K-Akt signaling pathway CSF3R,LAMC3,COMP,LOC608458,CSH2,CSF1R,CSH1,CSF1,PRP2,CDC37
    FoxO signaling pathway INS2,IL6,TGFB2,INS1,NLK,S1PR1,MAPK9,IGF1RB,RBL2,FOXO4
    Ion channel transport MCOLN2,TRPM1,ATP2B3A,SLC9B2,TSC22D3,ANO8,ATP13A,ANO10,ANO5B,CLCN1A
    Stimuli-sensing channels BEST1,ANO5B,TRPC4,CLCN4-2,TPCN1,ANO8,TRPA1B,MCOLN2,Ano3,CLCN5

    Protein Function

    SGK2 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.

    Function Related Protein
    sodium channel regulator activity SGK3,AGT,FXYD2,FGF12,SGK1,SCLT1,FXYD3,PTPN3,FXYD1,NOS1
    protein serine/threonine kinase activity KSR2,WNK2,cka1,PRKCDA,STK31,ACVR1L,RIOK1,TNNI3K,OXSR1B,SRPK3
    potassium channel regulator activity DRD2,KCNAB3,KCNMB3,LRRC26,DPP10,KCNE3,KCNS3,AKAP9,KCNMB4,SGK1
    calcium channel regulator activity Crisp4,CACNA2D1A,SGK2B,SGK3,TSPAN13,SGK2A,GRM3,STIM2,STIM1,CACNA2D2
    chloride channel regulator activity SGK1,CHRNA7,SGK2B,SLC9A3R1,SGK2A,SGK3,BSND
    ATP binding LYN,DDX59,FIGNL2,PDK4,NME2B.1,ACSM3,PRKAA2,ABCC1,EGFRA,TRNT1

    Interacting Protein

    SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.

    HSP90AB1;IL3RA;DDX5;TCP1;CCT6A;CCT5;CCT3;CCT8;CCT4;ILF3;FKBP5;CCT7

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