SGK2

  • Official Full Name

    serum/glucocorticoid regulated kinase 2

  • Overview

    Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort

  • Synonyms

    SGK2;serum/glucocorticoid regulated kinase 2;serine/threonine-protein kinase Sgk2;H-SGK2;dJ138B7.2

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Sf9 Cells
  • Mammalian Cells
  • HEK293
  • Insect Cells
  • Sf21 Cells
  • GST
  • His
  • T7
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway,Insulin Signaling,Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ion channel transport CLCNKA,FKBP1B,OSTM1,TRPM4C,TRPC5A,ATP1A1A.4,CLCA1,ATP10A,ATP13A1,GLRBA
    Transmembrane transport of small molecules ATP2C1,AQP8A.1,ATP13A,SLCO3A1,FTH1B,SLC2A10,ABCC9,SLC7A6,APOD,SLC30A1B
    Stimuli-sensing channels WNK1,TRPM1,OSTM1,CLCN4,CLCN1,TRPM4C,TRPC4APA,ANO8,ASPH,ANO1
    PI3K-Akt signaling pathway CSF3R,LAMC3,CSH,CSH1,EFNA2,LOC608458,PRP2,CSH2,CDC37,EFNA3
    Insulin Signaling GRB14,STXBP4,MAP3K9,RHOJ,MAP3K2,STXBP2,RRAD,STXBP3A,SNAP25A,MAP4K1
    FoxO signaling pathway Fasl,PRKAB1A,TNFSF10,NLK1,NLK2,MAPK14A,MAP2K2A,HRASB,PDPK1B,RBL2

    Protein Function

    SGK2 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.

    Function Related Protein
    potassium channel regulator activity ARPP19,NEDD4L,SGK2A,ABCC9,PRKCZ,KCNE1L,AMIGO1,KCNAB2,KCNAB3,KCNMB3
    chloride channel regulator activity SGK1,SGK3,CHRNA7,SGK2B,BSND,SGK2A,SLC9A3R1
    calcium channel regulator activity NRXN2,PRKG1,PLN,SRI,STIM1A,GRM6A,NPY2R,SGK1,Crisp4,GRM7
    ATP binding GATB,PAPOLB,STK31,RARS,EP400,MAP2K1,KIF26A,ABCB9,ACACB,JAK3
    sodium channel regulator activity AGT,YWHAH,SGK2B,PTPN3,PKP2,GPLD1,PRSS30,SCN3B,SCN2B,FXYD2
    protein serine/threonine kinase activity SLKA,GAK,ULK1A,PSKH2,BCR,STK11,PRKCBB,CSNK1G2A,BMPR1AA,STK35L

    Interacting Protein

    SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.

    HSP90AB1;IL3RA;DDX5;TCP1;CCT6A;CCT5;CCT3;CCT8;CCT4;ILF3;FKBP5;CCT7

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