SESN2
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Official Full Name
sestrin 2 -
Overview
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions. -
Synonyms
SESN2;sestrin 2;sestrin-2;DKFZp761M0212;HI95;SES2;SEST2;hypoxia induced gene 95;DKFZp761M02121
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- GST
- His
- His&T7
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
SESN2 involved in several pathways and played different roles in them. We selected most pathways SESN2 participated on our site, such as p signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SESN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| p signaling pathway | RCHY1,ATM,RRM2,SHISA5,CD82A,PTENA,RFWD2,STEAP3,CD82B,CASP9 |
Protein Function
SESN2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SESN2 itself. We selected most functions SESN2 had, and list some proteins which have the same functions with SESN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | AUNIP,DCTN2,DPH2,RABGAP1L,CRY1A,GNAI2,APC,GBP5,AURKB,CRTAC1 |
Interacting Protein
SESN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SESN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SESN2.
SQSTM1;Ulk1;Sqstm1;MDM2;ATG13;ULK1;RB1CC1
Resources
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References
- Brazina, J; Svadlenka, J; et al. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase. CELL CYCLE 14:375-387(2015).
- Yang, JH; Kim, KM; et al. Role of sestrin2 in the regulation of proinflammatory signaling in macrophages. FREE RADICAL BIOLOGY AND MEDICINE 78:156-167(2015).
