SERPINB5
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Official Full Name
serpin peptidase inhibitor, clade B (ovalbumin), member 5 -
Overview
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. -
Synonyms
SERPINB5;serpin peptidase inhibitor, clade B (ovalbumin), member 5;PI5;maspin;serpin B5;PI-5;peptidase inhibitor 5;protease inhibitor 5 (maspin);serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mouse
- HEK293T
- Non
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SERPINB5 involved in several pathways and played different roles in them. We selected most pathways SERPINB5 participated on our site, such as p signaling pathway,MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPINB5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| p signaling pathway | SIAH1A,GADD45AA,TP53I3,SESN2,CCNE1,RPRM,MDM2,PPM1DB,CCNB2,BAI1 |
| MicroRNAs in cancer | IKBKB,PDGFRA,TRP63,FZD3,MTOR,ITGB3,TNXB,SHC4,VEGFA,ZEB2 |
Protein Function
SERPINB5 has several biochemical functions, for example, protein binding,serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SERPINB5 itself. We selected most functions SERPINB5 had, and list some proteins which have the same functions with SERPINB5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TAF13,SMAP2,E2F8,ARF4,HOMEZ,POLR2E,NECAB3,RAP1GAP,METTL1,MTM1 |
| serine-type endopeptidase inhibitor activity | Serpina1b,SPINK12,PAPLN,SPINK10,MUG1,SERPINH1A,SERPINB9,PEBP1,SPINK3,SPINK1 |
Interacting Protein
SERPINB5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPINB5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPINB5.
PRSS21;Cdk1;XRCC3;BCAR3;KRAS;ESR1;AKT1;SMAD4;CASP8;STK11;PALB2;SLX4
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