SEC61G
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Official Full Name
Sec61 gamma subunit -
Overview
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified. -
Synonyms
SEC61G;Sec61 gamma subunit;protein transport protein Sec61 subunit gamma;SSS1;protein transport protein SEC61 gamma subunit
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Chicken
- Zebrafish
- Mus musculus
- Dog
- N-GST
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- Non
- His&Fc&Avi
Involved Pathway
SEC61G involved in several pathways and played different roles in them. We selected most pathways SEC61G participated on our site, such as Protein export,Protein processing in endoplasmic reticulum,Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC61G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | MARCH6,UBE2J1,HSP90B1,P4HB,CRYAB,TXNDC5,EIF2S1B,SSR3,HSP90AA1.1,EIF2AK1 |
| Protein export | SRP54A,HSPA5,SRP68,SEC11C,SRP54B,SRP9,SPCS3,ARXES2,SRP19,SEC61AL2 |
| Phagosome | ATP6V0A1B,TUBA1L,TUBA1A,SEC61AL2,TUBA1B,MHC1UXA2,DYNC1I2A,H2-AA,C3A.2,SEC22B |
| Vibrio cholerae infection | ATP6AP1,ATP6V1E2,ACTB,PLCG2,PDIA4,ATP6V0D1,ATP6V0A4,ATP6V1E1,ATP6V0A2,KDELR3 |
Protein Function
SEC61G has several biochemical functions, for example, P-P-bond-hydrolysis-driven protein transmembrane transporter activity,protein binding,protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC61G itself. We selected most functions SEC61G had, and list some proteins which have the same functions with SEC61G. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein transporter activity | TNPO2,COG3,XPO6,RUFY1,TSNAX,KPNA7,AP3S2,CHMP7,KPNA5,TNPO1 |
| protein binding | PIH1D1,RSRC2,WFDC9,GMNN,PHB,CTDSP2,KLF15,PIFO,LDB3,TSC22D1 |
| P-P-bond-hydrolysis-driven protein transmembrane transporter activity | TIMM44,TOMM20,TOMM20L,TIMM17B,TIMM23,TOMM20B,TIMM17A |
Interacting Protein
SEC61G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC61G here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC61G.
SFTPC;CREB3;pi3p
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