SCN1B
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Official Full Name
sodium channel, voltage-gated, type I, beta subunit
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Overview
SCN1B is a single-pass type I membrane protein abundantly expressed in skeletal muscle, heart and brain. The SCN1B forms part of a heterotrimeric complex of voltage-gated sodium channels involved in the generation and propagation of action potentials in m -
Synonyms
SCN1B; sodium channel, voltage-gated, type I, beta subunit; sodium channel, voltage gated, type I, beta , sodium channel, voltage gated, type I, beta polypeptide; sodium channel subunit beta-1; sodium channel beta-1 subunit; GEFSP1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Mus musculus (Mouse)
- Oryctolagus cuniculus (Rabbit)
- Pan troglodytes (Chimpanzee)
- Rat
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
SCN1B involved in several pathways and played different roles in them. We selected most pathways SCN1B participated on our site, such as Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCN1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adrenergic signaling in cardiomyocytes | CALML3;ADCY6;AGTR1;ATF4B1;CACNA1SB;PIK3CG;CALM2A;AKT2L;CREB3L1 |
SCN1B has several biochemical functions, for example, sodium channel inhibitor activity, sodium channel regulator activity, voltage-gated sodium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCN1B itself. We selected most functions SCN1B had, and list some proteins which have the same functions with SCN1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sodium channel inhibitor activity | NEDD4;PCSK9;NEDD4L;CAMK2D;SLC14A2;SCN1B |
| sodium channel regulator activity | NEDD4L;SCLT1;SCN1B;SCN3B;SCN1BA;PKP2;FGF13;SGK2B;FXYD3 |
| voltage-gated sodium channel activity | SCN8A;SCN12AB;HCN2;SCN4AA;PKD2;SCN11A;SCN1BB;SCN1LAB;SCN12AA |
| voltage-gated sodium channel activity involved in Purkinje myocyte action potential | SCN5A;SCN1B |
| voltage-gated sodium channel activity involved in cardiac muscle cell action potential | SCN3B;SCN1B;SCN5A;SCN2B |
SCN1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCN1B here. Most of them are supplied by our site. Hope this information will be useful for your research of SCN1B.
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