SCGB1D2
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Official Full Name
secretoglobin, family 1D, member 2 -
Overview
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. -
Synonyms
SCGB1D2;secretoglobin, family 1D, member 2;secretoglobin family 1D member 2;LIPB;lipophilin B (uteroglobin family member);prostatein like;LPHB;prostatein like lipophilin B;lipophilin-B;prostatein-like lipophilin B
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| SCGB1D2-1153H | Recombinant Human SCGB1D2 protein, His & GST-tagged | E.coli | Human | His&GST | Glu22~Val90 |
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| SCGB1D2-5253R | Recombinant Rat SCGB1D2 Protein | Mammalian Cells | Rat | His |
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| SCGB1D2-463H | Recombinant Human SCGB1D2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| SCGB1D2-4912R | Recombinant Rat SCGB1D2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SCGB1D2-4912R-B | Recombinant Rat SCGB1D2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| SCGB1D2-5362H | Recombinant Human SCGB1D2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
SCGB1D2 involved in several pathways and played different roles in them. We selected most pathways SCGB1D2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SCGB1D2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SCGB1D2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SCGB1D2 itself. We selected most functions SCGB1D2 had, and list some proteins which have the same functions with SCGB1D2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SCGB1D2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCGB1D2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SCGB1D2.
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References
- Sjodin, A; Guo, DS; et al. Secretoglobins in the human pituitary: high expression of lipophilin B and its down-regulation in pituitary adenomas. ACTA NEUROPATHOLOGICA 109:381-386(2005).
