SAG
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Official Full Name
SAG S-antigen; retina and pineal gland (arrestin) -
Overview
Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. -
Synonyms
SAG;S-antigen;retina and pineal gland (arrestin);S-arrestin;ARRESTIN;arrestin 1;48 kDa protein;rod photoreceptor arrestin;retinal S-antigen (48 KDa protein);RP47;S-AG;DKFZp686D1084;DKFZp686I1383
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Yeast
- Mammalian Cell
- HEK293
- HEK293T
- Mammalian cells
- His
- His&T7
- His&Fc&Avi
- Myc&DDK
- GST
- Flag
Involved Pathway
SAG involved in several pathways and played different roles in them. We selected most pathways SAG participated on our site, such as Phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SAG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phototransduction | RHO,CALML5,RGS9,GRK1B,GUCY2F,GNB1B,RCVRNA,RGS9B,GNAT1,CALM2B |
Protein Function
SAG has several biochemical functions, for example, opsin binding,phosphoprotein binding,protein phosphatase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SAG itself. We selected most functions SAG had, and list some proteins which have the same functions with SAG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphoprotein binding | PIH1D1,ARR3,SFN,SRC,RRAGA,MID1,YWHAE,URI1,LRP11,DPYS |
| protein phosphatase inhibitor activity | PHACTR1,PPP1R10,PPP1R2P3,PPME1,PPP1R27,GLC8,PHACTR3,ARPP19,DYSFIP1,ENSA |
| opsin binding | IFT20,ARR3 |
Interacting Protein
SAG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SAG here. Most of them are supplied by our site. Hope this information will be useful for your research of SAG.
ARRB2;ARRB1
Resources
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References
- Sullan, RMA; Li, JK; et al. Binding Forces of Streptococcus mutans P1 Adhesin. ACS NANO 9:1448-1460(2015).
- Batista, MT; Souza, RD; et al. Immunogenicity and In Vitro and In Vivo Protective Effects of Antibodies Targeting a Recombinant Form of the Streptococcus mutans P1 Surface Protein. INFECTION AND IMMUNITY 82:4978-4988(2014).
