S1PR3

  • Official Full Name

    sphingosine-1-phosphate receptor 3

  • Overview

    This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008]

  • Synonyms

    S1PR3;sphingosine-1-phosphate receptor 3;EDG3;LPB3;S1P3;EDG-3;sphingosine 1-phosphate receptor 3;S1P receptor 3;S1P receptor EDG3;S1P receptor Edg-3;sphingosine 1-phosphate receptor Edg-3;endothelial differentiation G-protein coupled receptor 3;G protein-coupled receptor, endothelial differentiation gene-3;endothelial differentiation, sphingolipid G-protein-coupled receptor, 3

Recombinant Proteins

  • Mouse
  • Human
  • Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • E.coli
  • In Vitro Cell Free System
  • His
  • Non
  • GST
  • Flag
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
S1PR3-14630M Recombinant Mouse S1PR3 Protein Mammalian Cells Mouse His
S1PR3-28463TH Recombinant Human S1PR3 Wheat Germ Human Non 77 amino acids
S1PR3-4040H Recombinant Human S1PR3 Protein, GST-tagged Wheat Germ Human GST
S1PR3-2084HCL Recombinant Human S1PR3 293 Cell Lysate HEK293 Human Non
RFL27572TF Recombinant Full Length Takifugu Rubripes Sphingosine 1-Phosphate Receptor 3(S1Pr3) Protein, His-Tagged E.coli Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) His Full L. Full Length (1-384)
RFL8305HF Recombinant Full Length Human Sphingosine 1-Phosphate Receptor 3(S1Pr3) Protein, His-Tagged E.coli Human His Full L. Full Length (1-378)
S1PR3-1119HFL Recombinant Human S1PR3 protein, His&Flag-tagged HEK293 Human Flag&His 1-378 aa
S1PR3-4726HF Recombinant Full Length Human S1PR3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 378 amino acids
S1PR3-7873M Recombinant Mouse S1PR3 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
S1PR3-7873M-B Recombinant Mouse S1PR3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    S1PR3 involved in several pathways and played different roles in them. We selected most pathways S1PR3 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with S1PR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    G alpha (i) signalling events CCR1,RGS10,HRH3,S1PR5B,ADRA2B,RGS19,RGS6,ANXA1B,CXCR7B,CCR3
    Class A/1 (Rhodopsin-like receptors) OPN5,PYY,INSL3,PROKR1,ACKR4,OXGR1A.2,NPFFR2,EDNRA,NMBB,DRD1
    Neuroactive ligand-receptor interaction MTNR1B,TAAR13D,GRID2,TACR2,TRY,TAAR14F,Chrng,SSTR2,TSHR,HTR5A
    Signal Transduction RGS1,LPAR5A,USP4,RHOT2,WWOX,C,SDR9C7,SEPT7,OR56A1,RTN4A
    GPCR downstream signaling OBSCN,RAMP3,DRD2,TRPC6A,PTHRP2,OPN5,TAS2R13,FPR-RS6,OR52J3,CASR
    GPCR ligand binding CRHB,RXFP2,SSTR1,GPR120,MLN,CCBP2,NMB,CCL35.2,LPAR2B,CXCR6
    Lysosphingolipid and LPA receptors S1PR5B,LPAR2B,LPAR2A,LPAR5A,S1PR1

    Protein Function

    S1PR3 has several biochemical functions, for example, G-protein coupled receptor activity,integrin binding,lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S1PR3 itself. We selected most functions S1PR3 had, and list some proteins which have the same functions with S1PR3. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity OPN4XA,TAAR1B,OR5V1,TAAR19P,ADORA2AA,PROKR2,TAS1R2.1,OR2AP1,OLFR507,TAS2R202
    sphingosine-1-phosphate receptor activity S1PR5,SPHK2,S1PR2,SPHK1,S1PR4,GPR6,S1PR5B,S1PR3A,S1PR5A,S1PR1
    lipid binding DLC1,FABP9,FAM123B,PAQR5B,FABP5,AP2M1B,CYTH4,FAM123A,CLINT1,ALOX15B
    integrin binding VWF,TNN,ITGB1,FAP,DST,WISP2,ADAM17,ITGA3,ADAM10,COL4A3
    protein binding THBS1,CHAMP1,PTPLAD1,RORC,PPP2CB,DPP4,AF251705,SAP18,KLRC4-KLRK1,NKX2-5

    Interacting Protein

    S1PR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S1PR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of S1PR3.

    ITGB4

    Resources

    Gene Families

    What is GPCR
    GPCRs Class A

    Research Area

    Endothelial Cell Development Molecules
    Endothelial Cell Markers
    Endothelial Cell Differentiation Markers

    References

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