RUNX1T1
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Official Full Name
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -
Overview
Vibrio cholerae is a motile gram negative curved rod shaped bacterium with a polar flagellum that causes cholera in humans. Serological typing of Vibrio cholerae is based on its O somatic antigens and it is classified in to more than 200 types. Of these, -
Synonyms
RUNX1T1;runt-related transcription factor 1;translocated to, 1 (cyclin D-related);AML1T1, CBFA2T1, core binding factor, runt domain, alpha subunit 2;translocated to, 1;cyclin D related;protein CBFA2T1;CDR;ETO;MTG8;ZMYND2;eight twenty one prote
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Myc
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RUNX1T1-2472H | Recombinant Human RUNX1T1, His-tagged | E.coli | Human | His | 1-351aa | |
| RUNX1T1-4600Z | Recombinant Zebrafish RUNX1T1 | Mammalian Cell | Zebrafish | His |
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| RUNX1T1-6309C | Recombinant Chicken RUNX1T1 | Mammalian Cell | Chicken | His |
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| RUNX1T1-2109HCL | Recombinant Human RUNX1T1 293 Cell Lysate | HEK293 | Human | Non |
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| RUNX1T1-2110HCL | Recombinant Human RUNX1T1 293 Cell Lysate | HEK293 | Human | Non |
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| RUNX1T1-1148H | Recombinant Human RUNX1T1 protein, His&Myc-tagged | E.coli | Human | His&Myc | 1-604aa |
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| RUNX1T1-2942H | Recombinant Human RUNX1T1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| RUNX1T1-701H | Recombinant Human RUNX1T1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Runx1t1-784M | Recombinant Mouse Runx1t1 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
RUNX1T1 involved in several pathways and played different roles in them. We selected most pathways RUNX1T1 participated on our site, such as Pathways in cancer,Transcriptional misregulation in cancer,Acute myeloid leukemia, which may be useful for your reference. Also, other proteins which involved in the same pathway with RUNX1T1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pathways in cancer | PLEKHG5,RARA,CSF3R,WNT11,FGF6,MMP1,STK4,GNAI2,CKS2,FGF8 |
| Acute myeloid leukemia | HRAS,CEBPA,PIK3CG,EIF4EBP1,SFPI1,NFKB1,SPI1,RAF1,KRAS,IKBKB |
| Transcriptional misregulation in cancer | IL3,WHSC1,ITGAM,PLAT,MAX,IL-8,SS18,SP1,LMO2,ZEB1 |
Protein Function
RUNX1T1 has several biochemical functions, for example, DNA binding,identical protein binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RUNX1T1 itself. We selected most functions RUNX1T1 had, and list some proteins which have the same functions with RUNX1T1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | SPI1B,KCNA3,RXRA,MLLT10,HMGB1,ZNF192,EVX1,NFE2L3,UBP1,POU6F2 |
| protein binding | PYGM,SGK3,DPCD,CRELD2,EIF1AY,BCS1L,LGALS9C,KLRK1,CUTA,BTG3 |
| DNA binding | ZFP451,NRL,RYBPA,SSRP1A,FOSL1A,POLR2H,ZFP239,HIST1H2AB,TBL1Y,HIST1H4C |
| transcription corepressor activity | HOXC6,TBL1Y,SAP30,CDYL,PFDN5,RELB,SP100,NCOR2,SKOR1,YWHAB |
| metal ion binding | STAMBP,MEP1A.1,VAV3,ZNF658,AOC1,TRIM35-35,PTGS1,ZNF728,KLF12,DPEP3 |
| identical protein binding | MTPAP,MTSS1,SMURF2,GOT2B,LYZ,CAV1,SID4,GPR50,HOOK3,TRIM39 |
Interacting Protein
RUNX1T1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RUNX1T1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RUNX1T1.
NCOR2;SP1;NCOR1;PSMD11;OTUD4;ZBTB16;HDAC1;ZNF652;THRAP3;LPXN;ATN1;C19orf57;CEP170P1;TAF9B
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References
- Fu, R; Liu, H; et al. Osteoblast inhibition by chemokine cytokine ligand3 in myeloma-induced bone disease. CANCER CELL INTERNATIONAL 14:-(2014).
- Kook, SH; Jeon, YM; et al. Periodontal Fibroblasts Modulate Proliferation and Osteogenic Differentiation of Embryonic Stem Cells Through Production of Fibroblast Growth Factors. JOURNAL OF PERIODONTOLOGY 85:645-654(2014).
