RP9
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Official Full Name
retinitis pigmentosa 9 (autosomal dominant) -
Overview
The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene. -
Synonyms
RP9;retinitis pigmentosa 9 (autosomal dominant);retinitis pigmentosa 9 protein;PAP 1;Pim 1 kinase associated protein;pim-1-associated protein;Pim-1 kinase associated protein;PAP-1
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RP9-2365H | Recombinant Human RP9, GST-tagged | E.coli | Human | GST | 1-221aa | |
| RP9-14385M | Recombinant Mouse RP9 Protein | Mammalian Cell | Mouse | His |
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| RP9-1742Z | Recombinant Zebrafish RP9 | Mammalian Cell | Zebrafish | His |
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| RP9-3958R | Recombinant Rhesus monkey RP9 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| RP9-7068H | Recombinant Human RP9, His-tagged | E.coli | Human | His | 1-155aa |
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| RP9-3775R | Recombinant Rhesus Macaque RP9 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| RP9-3775R-B | Recombinant Rhesus Macaque RP9 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| RP9-7710M | Recombinant Mouse RP9 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RP9-7710M-B | Recombinant Mouse RP9 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RP9 involved in several pathways and played different roles in them. We selected most pathways RP9 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RP9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | LSM5,SNRPE,U2SURP,U2AF2,HSC70,SF3B5,RBM25,CRNKL1,PUF60A,PRPF38A |
Protein Function
RP9 has several biochemical functions, for example, poly(A) RNA binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RP9 itself. We selected most functions RP9 had, and list some proteins which have the same functions with RP9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ITGB1,EIF1AY,BEX1,STX5,PIN4,VPS11,Ar,ZG16,USP34,PIM3 |
| poly(A) RNA binding | TBCA,LGALS3,ANKHD1,EEF1A1,RBMS2,DDX31,SCG3,RPL27,DDX41,TNPO1 |
| zinc ion binding | BTR16,RNF14,P2RX2,LIMS2,RNF113A,CA5,MMP19,SUV39H1B,MICALL2A,SEC24D |
Interacting Protein
RP9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RP9 here. Most of them are supplied by our site. Hope this information will be useful for your research of RP9.
PPP2CA;SRSF1
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References
- Lee, SH; Lillehoj, HS; et al. Development and characterization of mouse monoclonal antibodies reactive with chicken TL1A. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 159:103-109(2014).
- Jansen, CA; van de Haar, PM; et al. Identification of new populations of chicken natural killer (NK) cells. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 34:759-767(2010).
