RECQL
-
Official Full Name
RecQ helicase-like -
Overview
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5 and 3 UTRs, have been described. [provided by RefSeq, Jul 2008] -
Synonyms
RECQL;RecQ helicase-like;RecQ1;RECQL1;ATP-dependent DNA helicase Q1;recQ protein-like 1;DNA-dependent ATPase Q1;DNA helicase, RecQ-like type 1;RecQ protein-like (DNA helicase Q1-like)
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Chicken
- Mouse
- E.Coli/Yeast
- Mammalian Cells
- HEK293
- E.coli
- Insect Cells
- His
- Non
- Avi
- Fc
- DDK
- Myc
- Flag
Involved Pathway
RECQL involved in several pathways and played different roles in them. We selected most pathways RECQL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RECQL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RECQL has several biochemical functions, for example, ATP binding,ATP-dependent DNA helicase activity,DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RECQL itself. We selected most functions RECQL had, and list some proteins which have the same functions with RECQL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| annealing helicase activity | BLM,SMARCAL1,RAD54L,ANXA1,RECQL4,ZRANB3 |
| ATP-dependent DNA helicase activity | BLM,DHX9,DDX11,FBXO18,XRCC5,CHD4,WRN,RTEL1,DDX3X,G3BP1 |
| DNA binding | ZNF280D,TDP2B,RAG1,MSXB,TIGD6,THAP11,HOXD9A,TAF1A,ZNF461,ZNF18 |
| ATP binding | PEBP1,ASNS,MYH1B,CASK,cka1,MAPK10,YRK,GRK7B,PRKCHA,ABCB11 |
| DNA helicase activity | IGHMBP2,ATRX,DNA2,MCM3L,MCM2,FBXO18,MCM5,CHD8,RECQL5,RUVBL1 |
| protein binding | HHIPL2,NUDT1,AGBL4,WBP1L,GPRASP2,EIF2S2,HNRPDL,PRPF19,NEU2,WDR11 |
Interacting Protein
RECQL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RECQL here. Most of them are supplied by our site. Hope this information will be useful for your research of RECQL.
KPNA4;KPNA2;gag-pol;q81y32_bacan
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