RD3
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Official Full Name
retinal degeneration 3 -
Overview
This gene encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal degeneration. Alternative splicing results in multiple transcript variants. -
Synonyms
RD3;retinal degeneration 3;C1orf36, chromosome 1 open reading frame 36;protein RD3;LCA12;C1orf36;chromosome 1 open reading frame 36
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RD3-2234H | Recombinant Human RD3, His-tagged | E.coli | Human | His | 1-195aa | |
| RD3-5120Z | Recombinant Zebrafish RD3 | Mammalian Cells | Zebrafish | His |
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| RD3-2441HCL | Recombinant Human RD3 293 Cell Lysate | HEK293 | Human | Non |
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| RD3-2965H | Recombinant Human RD3 protein(1-195aa), His&Myc-tagged | E.coli | Human | N-His&C-Myc | 1-195aa |
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| Rd3-5442M | Recombinant Mouse Rd3 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| RD3-5664H | Recombinant Human RD3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
RD3 involved in several pathways and played different roles in them. We selected most pathways RD3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
RD3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RD3 itself. We selected most functions RD3 had, and list some proteins which have the same functions with RD3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PRKCI,XRCC1,KCNRG,RPS18,MAP2K4,ATXN7L3,CTBP2,CDC42SE2,DDR1,SPATA8 |
Interacting Protein
RD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RD3.
EHMT2;EIF2B1
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References
- Hara, M; Hirokawa, K; et al. Isoform transition from four-repeat to three-repeat tau underlies dendrosomatic and regional progression of neurofibrillary pathology. ACTA NEUROPATHOLOGICA 125:565-579(2013).
- Uchihara, T; Hara, M; et al. Tangle evolution linked to differential 3-and 4-repeat tau isoform deposition: a double immunofluorolabeling study using two monoclonal antibodies. HISTOCHEMISTRY AND CELL BIOLOGY 137:261-267(2012).
