RASA1
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Official Full Name
RAS p21 protein activator (GTPase activating protein) 1 -
Overview
The mammalian proto-oncogene Ras encodes 21 kDa proteins (p21Ras) which exists in either a physiologically quiescent GDP-binding state or a GTP binding signal-emitting state. Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolys -
Synonyms
RASA1;RAS p21 protein activator (GTPase activating protein) 1;RASA;ras GTPase-activating protein 1;capillary malformation arteriovenous malformation;CM AVM;GAP;p120GAP;p120RASGAP;triphosphatase-activating protein;PKWS;CMAVM;CM-AVM;RASGAP;DKFZp434N071
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- HEK293
- Wheat Germ
- Mammalian Cells
- GST
- Myc&DDK
- Non
- His
- His&T7
- His&Myc
- Flag
- His&Fc&Avi
Involved Pathway
RASA1 involved in several pathways and played different roles in them. We selected most pathways RASA1 participated on our site, such as MAPK signaling pathway,Ras signaling pathway,Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with RASA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | RHOD,PHB,MYL12B,SEMA3B,SHB,NADL1.1,CSF2RB,AGRN,FGF18B,RHOAE |
| Ras signaling pathway | PLD2,INS1,PLA2G10,PIK3R2,PLD1,BRAP,NRAS,SHC4,ANGPT4,PDGFRB |
| MAPK signaling pathway | KCNA3,MEF2C,PPM1BA,RAP1B,GADD45BB,MAPK14A,AKT3A,IL1B,Pdgfa&Pdgfb,PAK2 |
Protein Function
RASA1 has several biochemical functions, for example, GTPase activator activity,GTPase binding,glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RASA1 itself. We selected most functions RASA1 had, and list some proteins which have the same functions with RASA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glycoprotein binding | ITGA3,OS9,LGALS1,TFR2,EDEM2,B2M,FGFR1,FYN,FOXRED2,LACRT |
| GTPase binding | AIMP1,STOML2,BNIP3,SH3GL1,SPTBN1,EPRS,IARS,GM5506,PTPRN,GNB2 |
| potassium channel inhibitor activity | ENSA,KCNK2,NEDD4L,CAV3,PTI,KCNA5 |
| protein binding | FCGR2B,STXBP3A,ERC1,KCNRG,Tnfrsf23,EDC4,AMBRA1,HADHA,ATG4B,TMEM119 |
| GTPase activator activity | RIN1,RIN3,CHML,CDC42EP5,ARHGAP29B,AGAP5,NIPAL1,AGFG1B,TBC1D21,RGS14A |
| receptor binding | FGF6A,FGF1B,FGF12B,HCST,CCL13,LRP6,GSTM2,LTB,CCL2,PCSK1N |
Interacting Protein
RASA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RASA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RASA1.
DLC1;NCK1;PDGFRB;ERBB2
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