RAD54L
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Official Full Name
RAD54-like (S. cerevisiae) -
Overview
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein. -
Synonyms
RAD54L;RAD54-like (S. cerevisiae);RAD54 (S.cerevisiae) like;DNA repair and recombination protein RAD54-like;hHR54;hRAD54;RAD54A;RAD54 homolog;HR54
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- His
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RAD54L-11363Z | Recombinant Zebrafish RAD54L | Mammalian Cell | Zebrafish | His |
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| RAD54L-2552HCL | Recombinant Human RAD54L 293 Cell Lysate | HEK293 | Human | Non |
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| RAD54L-1549HFL | Recombinant Full Length Human RAD54L Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
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| RAD54L-1853H | Recombinant Human RAD54L Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| RAD54L-1853H-B | Recombinant Human RAD54L Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| RAD54L-390H | Recombinant Human RAD54L Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| RAD54L-5042H | Recombinant Human RAD54L Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Rad54l-5352M | Recombinant Mouse Rad54l Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
RAD54L involved in several pathways and played different roles in them. We selected most pathways RAD54L participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD54L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Homologous recombination | RAD51L3,CDK5R2,POLD2,RPA1,POLD1,FUZ,TOP3B,XRCC3,RPA2,RPA4 |
Protein Function
RAD54L has several biochemical functions, for example, ATP binding,DNA binding,annealing helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD54L itself. We selected most functions RAD54L had, and list some proteins which have the same functions with RAD54L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| helicase activity | SMARCAL1,GTF2F2A,CHD9,SUPV3L1,DHX32A,HELZ,ATRX,BAT1,HLTF,DHX34 |
| annealing helicase activity | ANXA1,ZRANB3,RECQL4,SMARCAL1,BLM,RECQL |
| ATP binding | Acsm2a,SEPHS2,SKIV2L2,TAF1,PRKCBB,PL10,SRPK3,PLK4,RENBP,STK35 |
| protein binding | MICAL1,TNFRSF1A,SZT2,MAPK8IP3,RXFP1,TRIM11,ZNF187,CIC,ELF4,PACS1 |
| DNA binding | BEND5,PARP1,LHX6,HOXA4,HIST1H4H,CEBPZ,LEF1,PRDM9,MYCA,MIER2 |
Interacting Protein
RAD54L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD54L here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD54L.
TNKS2;WDYHV1;NCK1;BAG6;LIMK1;Tecpr2;SGTB
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