RAD51D
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Official Full Name
RAD51 homolog D (S. cerevisiae) -
Overview
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, which are known to be involved in the homologous recombination and repair of DNA. This protein forms a complex with several other members of the RAD51 family, including RAD51L1, RAD51L2, and XRCC2. The protein complex formed with this protein has been shown to catalyze homologous pairing between single- and double-stranded DNA, and is thought to play a role in the early stage of recombinational repair of DNA. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream ring finger and FYVE-like domain containing 1 (RFFL) gene. -
Synonyms
RAD51-like 3 (S. cerevisiae);HsTRAD;R51H3;Trad;RAD51D;RAD51 (S. cerevisiae)-like 3;OTTHUMP00000163853;RAD51 homolog D;DNA repair protein RAD51 homolog 4;RAD51-like protein 3;recombination repair protein;RAD51L3;OTTHUMP00000163851;OTTHUMP00000163852;RAD51D;RAD51 homolog D (S. cerevisiae)
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
RAD51D-2156H | Recombinant Human RAD51D, GST-tagged | E.coli | Human | GST | 1-253aa | |
RAD51D-11807Z | Recombinant Zebrafish RAD51D | Mammalian Cell | Zebrafish | His | ||
RAD51D-411H | Recombinant Human RAD51 paralog D, His-tagged | E.coli | Human | His | 1-216 a.a. | |
RAD51D-4195C | Recombinant Chicken RAD51D | Mammalian Cell | Chicken | His | ||
RAD51D-448H | Recombinant Full Length Human RAD51 paralog D / RAD51D Protein, His-tagged | E.coli | Human | His | Full L. 1-328 a.a. | |
RAD51D-5049H | Recombinant Human RAD51D, His-tagged | E.coli | Human | His | ||
RAD51D-2553HCL | Recombinant Human RAD51L3 293 Cell Lysate | HEK293 | Human | Non | ||
RAD51D-3407H | Recombinant Full Length Human RAD51D Protein, GST-tagged | E.coli | Human | GST | Full L. 1-328aa |
Involved Pathway
RAD51D involved in several pathways and played different roles in them. We selected most pathways RAD51D participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD51D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Homologous recombination | RAD52,XRCC2,RPA2,MRE11A,RAD51L1,SYCP3,MUS81,POLD2,NBN,BLM |
Protein Function
RAD51D has several biochemical functions, for example, ATP binding,DNA binding,DNA-dependent ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD51D itself. We selected most functions RAD51D had, and list some proteins which have the same functions with RAD51D. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
DNA binding | ZNF556,NKX2.7,PBX1,PARPBP,NR5A2,NR0B1,HER6,BCLAF1,ZIC2,HOXB5B |
gamma-tubulin binding | CEP57L1,DIXDC1,RACGAP1,OFD1,B9D2,TUBGCP5,BLOC1S2,RAD51L3,NME2,TUBGCP4 |
contributes_to endodeoxyribonuclease activity | ERCC4,RAD51L1,RAD51,RAD51L3,RAD51B,DMC1,XRCC2 |
single-stranded DNA binding | HNRNPDL,RAD51L1,OBFC2B,SSBP2,RPA2,NABP1A,SUB1,HMGB1,NCL,CRY2 |
ATP binding | STRADA,VPS4B,GSS,EHD4,ATP2A2A,OPLAH,TGFBR1,TTK,ACSBG1,GTF2F2 |
double-stranded DNA binding | MEN1,PYDC3,RAD51AP1,TARDBP,TP53,XRCC3,DDX11,MTERF,MTERFD3,LSM14A |
contributes_to four-way junction DNA binding | XRCC2,MSH6,RAD51L1,XRCC3,RAD51C,MSH2,RAD51L3,RAD51B |
recombinase activity | RAD51L3,RAD51,XRCC2,XRCC3,RBPJ,RAD51B,RAD51L1,DMC1,RAD51C |
DNA-dependent ATPase activity | CHD8,RAD51C,IGHMBP2,ERCC2,SMARCAL1,MSH4,DDX11,CHD6,MSH6,CDK7 |
Interacting Protein
RAD51D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD51D here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD51D.
XRCC2
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