RAB11B
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Official Full Name
RAB11B, member RAS oncogene family -
Overview
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho;(see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of;essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating;exocytotic and endocytotic pathways (summary by Zhu et al., 1994 (PubMed 7811277)). -
Synonyms
RAB11B;RAB11B, member RAS oncogene family;ras-related protein Rab-11B;H YPT3;GTP-binding protein YPT3;RAB11B, member of RAS oncogene family;H-YPT3;MGC133246
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Flag
- His&Fc&Avi
- GST
- Myc&DDK
Involved Pathway
RAB11B involved in several pathways and played different roles in them. We selected most pathways RAB11B participated on our site, such as Endocytosis,AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB11B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| AMPK signaling pathway | PIK3CG,PPP2R2C,PPP2CA,EEF2K,CAB39,PPP2R2D,SCD5,PPP2R2B,IGF1,RPS6KB1 |
| Endocytosis | EHD4,WIPF2B,GBF1,CHMP2A,FOLR2,CXCR4A,VPS45,FOLR1,DDL-2,RAB11FIP3 |
Protein Function
RAB11B has several biochemical functions, for example, GDP binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB11B itself. We selected most functions RAB11B had, and list some proteins which have the same functions with RAB11B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GDP binding | RAB8A,PRPS2,RAB12,RHOB,RAB3B,RALB,PRPS1,RAB9B,RAB40C,RAB7A |
| GTP binding | GNAS,GMPPAA,RAP2AB,RHOGC,MTG1,GUCY2C,DAPK1,RAB5AB,RAB3C,GTPBP1 |
| myosin V binding | RAB39B,RAB27A,RAB11A,RAB10,RAB27B,RAB6A,RAB14,RAB6B,FUS,RAB3B |
| protein binding | CLTC,PRPF40A,CEP70,PICK1,RMND5A,TICAM1,EIF4G1,ADCK5,ELAVL1,ZGPAT |
| GTPase activity | RAB14L,GNG5,EIF2S3,RAB14,GFM1,GNB5,DNM3A,RHOA,RRAS,RRAGA |
Interacting Protein
RAB11B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB11B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB11B.
TBC1D14;EPB41;OLFM2;SREBF2;pi3p;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;ATP6AP2;FN1;H2AFX;JAK3;Rab11a;CLTC;Crocc;Rcc1;Klc3;Rab11fip1;Snap29;GOLT1B;IKBKG
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References
- Gallo, LI; Liao, Y; et al. TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells. MOLECULAR BIOLOGY OF THE CELL 25:3779-3797(2014).
- Reger, AS; Yang, MP; et al. Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions. JOURNAL OF BIOLOGICAL CHEMISTRY 289:25393-25403(2014).
